Primary carcinoma of the small intestine. A clinicopathologic and immunohistochemical study

G. S. Lien, M. Mori, M. Enjoji

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

A clinicopathologic and immunohistochemical study of fifty-two primary carcinomas of the small intestine (20 duodenal, 18 jejunal, and 14 ileal) was performed. Most of these neoplasms were located in the proximal duodenum, proximal jejunum, and distal ileum. Most of these tumors produced both sialomucin and sulfomucin, although the adjacent mucosa showed hyperplastic changes with increased sialomucin secretion. Argyrophil cells were recognized in seven duodenal (35%), 13 jejunal (72%), and nine ileal (69%) carcinomas. Eighteen of the 29 tumors showing positive argyrophil reactions also had argentaffin cells. The common features of mucins and endocrine cells in these tumors suggest that embryonic antigen (CEA) grading, invading pattern of tumor margins, and vascular permeation and regional lymph node metastasis.

Original languageEnglish
Pages (from-to)316-323
Number of pages8
JournalCancer
Volume61
Issue number2
Publication statusPublished - 1988
Externally publishedYes

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Small Intestine
Carcinoma
Sialomucins
Neoplasms
Enterochromaffin Cells
Endocrine Cells
Mucins
Jejunum
Ileum
Duodenum
Blood Vessels
Mucous Membrane
Lymph Nodes
Neoplasm Metastasis
Antigens

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Primary carcinoma of the small intestine. A clinicopathologic and immunohistochemical study. / Lien, G. S.; Mori, M.; Enjoji, M.

In: Cancer, Vol. 61, No. 2, 1988, p. 316-323.

Research output: Contribution to journalArticle

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