Primary adrenal insufficiency in patients with acquired immunodeficiency syndrome: Report of four cases

Yi Wen Huang, Ching Chung Chang, Hsin Yun Sun, Mao Yuan Chen, Chien Ching Hung, Shan Chwen Chang

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Adrenal insufficiency, though rare, is a well-known complication of acquired immunodeficiency syndrome (AIDS). Over the past 9 years at the National Taiwan University Hospital, 4 patients were diagnosed with primary adrenal insufficiency among 854 non-hemophiliac patients with human immunodeficiency virus infection, with an incidence of 0.19 per 100 patient-years (95% confidence interval, 0.17-0.21 per 100 patient-years). All of the 4 patients were severely immunosuppressed and had been diagnosed with at least 1 AIDS-defining opportunistic illness ever reported to produce adrenal insufficiency in AIDS patients. In 1 of the patients, fluconazole was considered contributory to the development of adrenal insufficiency after treatment at a daily dose of 800 mg for 68 days.

Original languageEnglish
Pages (from-to)250-253
Number of pages4
JournalJournal of Microbiology, Immunology and Infection
Volume37
Issue number4
Publication statusPublished - Aug 2004
Externally publishedYes

Keywords

  • Acquired immunodeficiency syndrome
  • Adrenal gland diseases
  • Opportunistic infections
  • Pneumocystis pneumonia

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

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