Prevalence of spondyloarthritis in 504 Chinese patients with HLA-B27-associated acute anterior uveitis

Yu-mei Chung, Hsien-Tzung Liao, Kuan Chia Lin, Y. C. Lin, Chung Tei Chou, Chun Hsiung Chen, C. P. Tsai

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Objectives: To estimate the prevalence of spondyloarthritis (SpA) and the clinical features of human leucocyte antigen (HLA)-B27-associated acute anterior uveitis (HLA-B27 uveitis) in Chinese patients. Methods: We conducted a retrospective cohort study using a structured chart review to record the complete ocular history, including the onset of uveitis, month of uveitis attack, specific eye involvement, the time of first attack, and rheumatic manifestations from 1987 to 2004. A total of 504 patients with HLA-B27 uveitis were consequently enrolled consecutively from the uveitis clinic of Taipei Veterans General Hospital. Results: In total, 1719 attacks of uveitis in 504 patients were recorded. Females tended to have a higher frequency of attack than males, and those with a disease course of less than 5 years showed more uveitis recurrence. The same eye attacks were observed in 156 of 332 patients (47%), more than the expected percentage compared with attacks with random-eye occurrence (p

Original languageEnglish
Pages (from-to)84-90
Number of pages7
JournalScandinavian Journal of Rheumatology
Volume38
Issue number2
DOIs
Publication statusPublished - 2009

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

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