Prevalence of methicillin-resistant Staphylococcus aureus nasal colonization among Taiwanese children in 2005 and 2006

Yhu Chering Huang, Kao Pin Hwang, Po Yen Chen, Chih Jung Chen, Tzou Yien Lin

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Abstract

From July 2005 to October 2006, a total of 3,046 children, of ages between 2 months and 5 years, presented for a well-child health care visit to one of three medical centers, which are located in the northern, central, and southern parts of Taiwan, and were surveyed for nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA). The overall prevalences of S. aureus and MRSA nasal carriage among the children were 23% and 7.3%, respectively (18% and 4.8% in the central region, 25% and 6.7% in the southern region, and 27% and 9.5% in the northern region). Of the 212 MRSA isolates (96%) available for analysis, a total of 10 pulsed-field gel electrophoresis (PFGE) patterns with two major patterns (C [61%] and D [28%]) were identified. One hundred forty-nine isolates (70%) contained type IV staphylococcal cassette chromosome mec (SCCmec) DNA, and 55 isolates (26%) contained SCCmec VT. The presence of Panton-Valentine Leukocidin (PVL) genes was detected in 60 isolates (28%). Most MRSA isolates belonged to one of two major clones, characterized as sequence type 59 (ST59)/PFGE C/SCCmec IV/absence of PVL genes (59%) and ST59/PFGE D/SCCmec VT/presence of PVL genes (25%). We concluded that between 2005 and 2006, 7.3% of healthy Taiwanese children were colonized by MRSA in nares. MRSA harbored in healthy children indicates an accelerated spread in the community.

Original languageEnglish
Pages (from-to)3992-3995
Number of pages4
JournalJournal of Clinical Microbiology
Volume45
Issue number12
DOIs
Publication statusPublished - Dec 2007
Externally publishedYes

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Methicillin-Resistant Staphylococcus aureus
Nose
Pulsed Field Gel Electrophoresis
Chromosomes
Genes
Child Care
Taiwan
Staphylococcus aureus
Clone Cells
Delivery of Health Care
DNA
Panton-Valentine leukocidin

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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Prevalence of methicillin-resistant Staphylococcus aureus nasal colonization among Taiwanese children in 2005 and 2006. / Huang, Yhu Chering; Hwang, Kao Pin; Chen, Po Yen; Chen, Chih Jung; Lin, Tzou Yien.

In: Journal of Clinical Microbiology, Vol. 45, No. 12, 12.2007, p. 3992-3995.

Research output: Contribution to journalArticle

Huang, Yhu Chering ; Hwang, Kao Pin ; Chen, Po Yen ; Chen, Chih Jung ; Lin, Tzou Yien. / Prevalence of methicillin-resistant Staphylococcus aureus nasal colonization among Taiwanese children in 2005 and 2006. In: Journal of Clinical Microbiology. 2007 ; Vol. 45, No. 12. pp. 3992-3995.
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