Prevalence of human immunodeficiency virus and its association with hepatitis B, C, and D virus infections among incarcerated male substance abusers in Taiwan

Fang Yeh Chu, Shu Chuan Chiang, Fu Hsiung Su, Yuan Ying Chang, Shu Hsing Cheng

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Taiwan has been facing a rising epidemic of human immunodeficiency virus (HIV) infection since 2004. Injection drug users comprised 38.5% of accumulated HIV cases by 2007. This cross-sectional study investigated the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), and HIV infection in 753 male substance users who were detained in a detoxification center in Taoyuan, Taiwan. The subjects were enrolled into the study consecutively between February and October, 2005. The seroprevalence rates of HIV antibodies, HCV antibodies, and HBV surface antigens among all subjects, and HDV antibodies among HBV carriers were 6.9% (95% confidence interval [CI]: 5.19-8.95), 30.5% (95% CI: 27.23-33.93), 16.9% (95% CI: 14.24-19.71) and 13.7% (95% CI: 8.19-21.04), respectively. Subjects in the heroin injection group had significantly higher rates of HIV infection, HCV infection and HDV superinfection (25.5%, 89.6%, and 38.7%) than those in the heroin non-injection group (0.9%, 24.5%, and 6.25%), the methamphetamine group (0.3%, 8.1%, and 6.7%), and the club drug group (1%, 3%, and 0%; P

Original languageEnglish
Pages (from-to)973-978
Number of pages6
JournalJournal of Medical Virology
Volume81
Issue number6
DOIs
Publication statusPublished - Jun 2009
Externally publishedYes

Fingerprint

Hepatitis Delta Virus
Virus Diseases
Taiwan
Hepatitis B virus
Hepacivirus
HIV
Confidence Intervals
Heroin
Seroepidemiologic Studies
Hepatitis B Antibodies
Superinfection
Injections
Hepatitis C Antibodies
Methamphetamine
Hepatitis B Surface Antigens
Drug Users
Cross-Sectional Studies
Antibodies
Pharmaceutical Preparations

Keywords

  • Hepatitis
  • Heroin
  • HIV
  • Injections
  • Substance abuse
  • Taiwan

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

Cite this

Prevalence of human immunodeficiency virus and its association with hepatitis B, C, and D virus infections among incarcerated male substance abusers in Taiwan. / Chu, Fang Yeh; Chiang, Shu Chuan; Su, Fu Hsiung; Chang, Yuan Ying; Cheng, Shu Hsing.

In: Journal of Medical Virology, Vol. 81, No. 6, 06.2009, p. 973-978.

Research output: Contribution to journalArticle

Chu, Fang Yeh ; Chiang, Shu Chuan ; Su, Fu Hsiung ; Chang, Yuan Ying ; Cheng, Shu Hsing. / Prevalence of human immunodeficiency virus and its association with hepatitis B, C, and D virus infections among incarcerated male substance abusers in Taiwan. In: Journal of Medical Virology. 2009 ; Vol. 81, No. 6. pp. 973-978.
@article{9c693051d1514f03a46f4e8fe6e2038f,
title = "Prevalence of human immunodeficiency virus and its association with hepatitis B, C, and D virus infections among incarcerated male substance abusers in Taiwan",
abstract = "Taiwan has been facing a rising epidemic of human immunodeficiency virus (HIV) infection since 2004. Injection drug users comprised 38.5{\%} of accumulated HIV cases by 2007. This cross-sectional study investigated the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), and HIV infection in 753 male substance users who were detained in a detoxification center in Taoyuan, Taiwan. The subjects were enrolled into the study consecutively between February and October, 2005. The seroprevalence rates of HIV antibodies, HCV antibodies, and HBV surface antigens among all subjects, and HDV antibodies among HBV carriers were 6.9{\%} (95{\%} confidence interval [CI]: 5.19-8.95), 30.5{\%} (95{\%} CI: 27.23-33.93), 16.9{\%} (95{\%} CI: 14.24-19.71) and 13.7{\%} (95{\%} CI: 8.19-21.04), respectively. Subjects in the heroin injection group had significantly higher rates of HIV infection, HCV infection and HDV superinfection (25.5{\%}, 89.6{\%}, and 38.7{\%}) than those in the heroin non-injection group (0.9{\%}, 24.5{\%}, and 6.25{\%}), the methamphetamine group (0.3{\%}, 8.1{\%}, and 6.7{\%}), and the club drug group (1{\%}, 3{\%}, and 0{\%}; P",
keywords = "Hepatitis, Heroin, HIV, Injections, Substance abuse, Taiwan",
author = "Chu, {Fang Yeh} and Chiang, {Shu Chuan} and Su, {Fu Hsiung} and Chang, {Yuan Ying} and Cheng, {Shu Hsing}",
year = "2009",
month = "6",
doi = "10.1002/jmv.21481",
language = "English",
volume = "81",
pages = "973--978",
journal = "Journal of Medical Virology",
issn = "0146-6615",
publisher = "Wiley-Liss Inc.",
number = "6",

}

TY - JOUR

T1 - Prevalence of human immunodeficiency virus and its association with hepatitis B, C, and D virus infections among incarcerated male substance abusers in Taiwan

AU - Chu, Fang Yeh

AU - Chiang, Shu Chuan

AU - Su, Fu Hsiung

AU - Chang, Yuan Ying

AU - Cheng, Shu Hsing

PY - 2009/6

Y1 - 2009/6

N2 - Taiwan has been facing a rising epidemic of human immunodeficiency virus (HIV) infection since 2004. Injection drug users comprised 38.5% of accumulated HIV cases by 2007. This cross-sectional study investigated the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), and HIV infection in 753 male substance users who were detained in a detoxification center in Taoyuan, Taiwan. The subjects were enrolled into the study consecutively between February and October, 2005. The seroprevalence rates of HIV antibodies, HCV antibodies, and HBV surface antigens among all subjects, and HDV antibodies among HBV carriers were 6.9% (95% confidence interval [CI]: 5.19-8.95), 30.5% (95% CI: 27.23-33.93), 16.9% (95% CI: 14.24-19.71) and 13.7% (95% CI: 8.19-21.04), respectively. Subjects in the heroin injection group had significantly higher rates of HIV infection, HCV infection and HDV superinfection (25.5%, 89.6%, and 38.7%) than those in the heroin non-injection group (0.9%, 24.5%, and 6.25%), the methamphetamine group (0.3%, 8.1%, and 6.7%), and the club drug group (1%, 3%, and 0%; P

AB - Taiwan has been facing a rising epidemic of human immunodeficiency virus (HIV) infection since 2004. Injection drug users comprised 38.5% of accumulated HIV cases by 2007. This cross-sectional study investigated the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), and HIV infection in 753 male substance users who were detained in a detoxification center in Taoyuan, Taiwan. The subjects were enrolled into the study consecutively between February and October, 2005. The seroprevalence rates of HIV antibodies, HCV antibodies, and HBV surface antigens among all subjects, and HDV antibodies among HBV carriers were 6.9% (95% confidence interval [CI]: 5.19-8.95), 30.5% (95% CI: 27.23-33.93), 16.9% (95% CI: 14.24-19.71) and 13.7% (95% CI: 8.19-21.04), respectively. Subjects in the heroin injection group had significantly higher rates of HIV infection, HCV infection and HDV superinfection (25.5%, 89.6%, and 38.7%) than those in the heroin non-injection group (0.9%, 24.5%, and 6.25%), the methamphetamine group (0.3%, 8.1%, and 6.7%), and the club drug group (1%, 3%, and 0%; P

KW - Hepatitis

KW - Heroin

KW - HIV

KW - Injections

KW - Substance abuse

KW - Taiwan

UR - http://www.scopus.com/inward/record.url?scp=66449124039&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=66449124039&partnerID=8YFLogxK

U2 - 10.1002/jmv.21481

DO - 10.1002/jmv.21481

M3 - Article

VL - 81

SP - 973

EP - 978

JO - Journal of Medical Virology

JF - Journal of Medical Virology

SN - 0146-6615

IS - 6

ER -