Prevalence of and risk factors for nasal methicillin-resistant Staphylococcus aureus colonization among children in central Taiwan

Hui Hsien Pan, Yhu Chering Huang, Chih Jung Chen, Fang Liang Huang, Pei Ju Ting, Jing Yang Huang, Cheng Hsun Chiu, Tzou-Yien Lin, Po Yen Chen

Research output: Contribution to journalArticle

Abstract

Background/purpose: Staphylococcus aureus (S. aureus) causes diseases ranging from mild skin infections to invasive diseases. Carriage of S. aureus, including methicillin-resistant S. aureus (MRSA), is a significant risk factor for subsequent staphylococcal infection. Several studies discussed MRSA colonization in Taiwan, but mostly in northern Taiwan. This is the first study that estimates the prevalence of MRSA nasal colonization in healthy children and identifies the potential risk factors in central Taiwan. Methods: A total of 3144 healthy children aged 2–60 months who visited Taichung Veterans General Hospital (TCVGH) were screened for nasal S. aureus carriage from July 2005 to December 2010. Questionnaires included demographic information and potential risk factors for carriage of S. aureus were completed by parents/guardians. Results: Prevalence of MSSA and MRSA were 12.09% and 5.25%, respectively. The youngest group aged 2–6 months had the highest S. aureus carriage rate, and the carriage rate revealed a peak in summer. The nasal colonization of Streptococcus pneumoniae (S. pneumoniae) was a protective factor against S. aureus colonization. 85% of the MRSA colonizing isolates belonged to clonal complex 59/staphylococcal cassette chromosome type IV or VT, the local community clone in Taiwan. Conclusion: An increasing trend of MRSA nasal carriage rate in Taiwan had been brought forward, however, it was not observed in central Taiwan during the period of 2005–2010. We found a summer peak on both MRSA and MSSA carriages.

Original languageEnglish
JournalJournal of Microbiology, Immunology and Infection
DOIs
Publication statusAccepted/In press - Jan 1 2018
Externally publishedYes

Fingerprint

Methicillin-Resistant Staphylococcus aureus
Taiwan
Nose
Staphylococcus aureus
Veterans Hospitals
Staphylococcal Infections
Streptococcus pneumoniae
General Hospitals
Clone Cells
Cross-Sectional Studies
Chromosomes
Parents
Demography
Skin
Infection

Keywords

  • Central Taiwan
  • Children
  • Methicillin-resistant Staphylococcus aureus colonization

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Prevalence of and risk factors for nasal methicillin-resistant Staphylococcus aureus colonization among children in central Taiwan. / Pan, Hui Hsien; Huang, Yhu Chering; Chen, Chih Jung; Huang, Fang Liang; Ting, Pei Ju; Huang, Jing Yang; Chiu, Cheng Hsun; Lin, Tzou-Yien; Chen, Po Yen.

In: Journal of Microbiology, Immunology and Infection, 01.01.2018.

Research output: Contribution to journalArticle

Pan, Hui Hsien ; Huang, Yhu Chering ; Chen, Chih Jung ; Huang, Fang Liang ; Ting, Pei Ju ; Huang, Jing Yang ; Chiu, Cheng Hsun ; Lin, Tzou-Yien ; Chen, Po Yen. / Prevalence of and risk factors for nasal methicillin-resistant Staphylococcus aureus colonization among children in central Taiwan. In: Journal of Microbiology, Immunology and Infection. 2018.
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