Prevalence of and risk factors for colonization by methicillin-resistant Staphylococcus aureus among adults in community Settings in Taiwan

Jann Tay Wang, Chun Hsing Liao, Chi Tai Fang, Wei Chu Chie, Mei Shu Lai, Tsai Ling Lauderdale, Wen Sen Lee, Jeng Hua Huang, Shan Chwen Chang

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

In order to determine the prevalence of methicillin (meticillin)-resistant Staphylococcus aureus (MRSA) colonization among adults in community settings in Taiwan and identify its risk factors, we conducted the present study. For a 3-month period, we enrolled all adults who attended mandatory health examinations at three medical centers and signed the informed consent. Nasal swabs were taken for the isolation of S. aureus. For each MRSA isolate, we performed multilocus sequence typing, identification of the staphylococcal cassette chromosome mec, tests for the presence of the Panton-Valentine leukocidin gene, and tests for drug susceptibilities. Risk factors for MRSA colonization were determined. The results indicated that the MRSA colonization rate among adults in the community settings in Taiwan was 3.8% (119/3,098). Most MRSA isolates belonged to sequence type 59 (84.0%). Independent risk factors for MRSA colonization included the presence of household members less than 7 years old (P <0.0001) and the use of antibiotics within the past year (P = 0.0031). Smoking appeared to be protective against MRSA colonization (P <0.0001).

Original languageEnglish
Pages (from-to)2957-2963
Number of pages7
JournalJournal of Clinical Microbiology
Volume47
Issue number9
DOIs
Publication statusPublished - Sep 2009

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Methicillin-Resistant Staphylococcus aureus
Methicillin
Taiwan
Staphylococcus aureus
Multilocus Sequence Typing
Informed Consent
Nose
Chromosomes
Smoking
Anti-Bacterial Agents
Health
Pharmaceutical Preparations
Genes

ASJC Scopus subject areas

  • Microbiology (medical)

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Prevalence of and risk factors for colonization by methicillin-resistant Staphylococcus aureus among adults in community Settings in Taiwan. / Wang, Jann Tay; Liao, Chun Hsing; Fang, Chi Tai; Chie, Wei Chu; Lai, Mei Shu; Lauderdale, Tsai Ling; Lee, Wen Sen; Huang, Jeng Hua; Chang, Shan Chwen.

In: Journal of Clinical Microbiology, Vol. 47, No. 9, 09.2009, p. 2957-2963.

Research output: Contribution to journalArticle

Wang, Jann Tay ; Liao, Chun Hsing ; Fang, Chi Tai ; Chie, Wei Chu ; Lai, Mei Shu ; Lauderdale, Tsai Ling ; Lee, Wen Sen ; Huang, Jeng Hua ; Chang, Shan Chwen. / Prevalence of and risk factors for colonization by methicillin-resistant Staphylococcus aureus among adults in community Settings in Taiwan. In: Journal of Clinical Microbiology. 2009 ; Vol. 47, No. 9. pp. 2957-2963.
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