Pressor effect on blood pressure and renal nerve activity elicited by electroacupuncture in intact and acute hemorrhage rats

Hua Ting, Jiuan Miaw Liao, Chih Feng Lin, Ping Yen Chiang, Chi Chen Chang, Dong Yih Kuo, Tzer Bin Lin

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The neural mechanism underlying the effect of electroacupuncture (Ea) on arterial blood pressure (BP) and renal nerve activity (RNA) in the intact state and during acute hemorrhage was investigated in anesthetized rats. Two acupoints, Hoku (Li-4, at the junction of the first and the second metacarpal bone) and Tsusanli (St-36, at the lateral upper tibia bone), were tested using Ea of two different frequencies (2 and 20 Hz). In the intact state, Ea at Hoku elicited an elevation of BP in parallel with RNA, while Ea found no response with identical parameters at Tsusanli. The pattern of the pressor response caused by a low frequency Ea (2 Hz) at Hoku was different than a high frequency one (20 Hz), i.e. a tonic effect was elicited with 2 Hz, while a phasic one was induced with 20 Hz. In mild hemorrhage conditions (10% of BP decrease), similar pressor effects, as in intact rats, were also elicited by Ea. However, in severe hemorrhage conditions (20 and 30% BP decrease), Ea induced a pressor effect on RNA and an attenuated effect on BP. BP and RNA showed a significant correlation in intact and mild hemorrhage conditions, but not in severe hemorrhage conditions. All the results suggested that Ea at Hoku with appropriate stimulation parameters can increase and maintain BP in normal and hemorrhage conditions, and such a therapeutic technique has potential in clinical practice.

Original languageEnglish
Pages (from-to)5-8
Number of pages4
JournalNeuroscience Letters
Volume327
Issue number1
DOIs
Publication statusPublished - Jul 12 2002
Externally publishedYes

Fingerprint

Electroacupuncture
Hemorrhage
Blood Pressure
Kidney
Acupuncture Points
Metacarpal Bones
Tibia
Arterial Pressure
Bone and Bones

Keywords

  • Blood pressure
  • Electroacupuncture
  • Hemorrhage
  • Rat
  • Renal nerve

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Pressor effect on blood pressure and renal nerve activity elicited by electroacupuncture in intact and acute hemorrhage rats. / Ting, Hua; Liao, Jiuan Miaw; Lin, Chih Feng; Chiang, Ping Yen; Chang, Chi Chen; Kuo, Dong Yih; Lin, Tzer Bin.

In: Neuroscience Letters, Vol. 327, No. 1, 12.07.2002, p. 5-8.

Research output: Contribution to journalArticle

Ting, Hua ; Liao, Jiuan Miaw ; Lin, Chih Feng ; Chiang, Ping Yen ; Chang, Chi Chen ; Kuo, Dong Yih ; Lin, Tzer Bin. / Pressor effect on blood pressure and renal nerve activity elicited by electroacupuncture in intact and acute hemorrhage rats. In: Neuroscience Letters. 2002 ; Vol. 327, No. 1. pp. 5-8.
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