Abstract
Purpose: This study aimed to investigate the most prescribed medications and principle diagnoses for category D and X drugs during pregnancy using a population-based dataset in Taiwan. Methods: The data for the present study were sourced from the Taiwan Longitudinal Health Insurance Database 2000. We selected 14125 women who had live singleton births between 1 January 2009 and 31 December 2011. In total, 217226 prescriptions prescribed to these pregnant women were identified. Results: Of the total 217226 prescriptions, 1.1% were category D or X drugs; in the first, second, and third trimesters of pregnancy, 1.8%, 0.7%, and 0.5% of prescriptions were category D or X drugs, respectively. Progestins (15.3%) and propylthiouracil (10.7%) were the two most frequently prescribed category D or X drugs during pregnancy. In particular, progestins (20.4%) and estrogens (15.6%) were the most frequently prescribed category D or X drug in the first trimester of pregnancy. Propylthiouracil was the most prescribed category D or X drug in the second (20.3%) and third trimesters (23.1%) of pregnancy, respectively. The most common principal diagnosis during pregnancy was "disorders of menstruation and other abnormal bleeding from the female genital tract" (22% of all principal diagnoses for prescribing category D and X drugs). Conclusions: Our study found that the physicians obviously reduced the use of category D and X drugs for women after becoming aware that they were pregnant. Copyright
| Original language | English |
|---|---|
| Pages (from-to) | 1029-1034 |
| Number of pages | 6 |
| Journal | Pharmacoepidemiology and Drug Safety |
| Volume | 23 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 1 2014 |
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Keywords
- Category D and X drugs
- Pharmacoepidemiology
- Pregnancy
- Prescribing behavior
ASJC Scopus subject areas
- Pharmacology (medical)
- Epidemiology
- Medicine(all)
Cite this
Prescriptions for category D and X drugs during pregnancy in Taiwan : A population-based study. / Kao, Li Ting; Chen, Yi Hua; Lin, Herng Ching; Chung, Shiu Dong.
In: Pharmacoepidemiology and Drug Safety, Vol. 23, No. 10, 01.10.2014, p. 1029-1034.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prescriptions for category D and X drugs during pregnancy in Taiwan
T2 - A population-based study
AU - Kao, Li Ting
AU - Chen, Yi Hua
AU - Lin, Herng Ching
AU - Chung, Shiu Dong
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Purpose: This study aimed to investigate the most prescribed medications and principle diagnoses for category D and X drugs during pregnancy using a population-based dataset in Taiwan. Methods: The data for the present study were sourced from the Taiwan Longitudinal Health Insurance Database 2000. We selected 14125 women who had live singleton births between 1 January 2009 and 31 December 2011. In total, 217226 prescriptions prescribed to these pregnant women were identified. Results: Of the total 217226 prescriptions, 1.1% were category D or X drugs; in the first, second, and third trimesters of pregnancy, 1.8%, 0.7%, and 0.5% of prescriptions were category D or X drugs, respectively. Progestins (15.3%) and propylthiouracil (10.7%) were the two most frequently prescribed category D or X drugs during pregnancy. In particular, progestins (20.4%) and estrogens (15.6%) were the most frequently prescribed category D or X drug in the first trimester of pregnancy. Propylthiouracil was the most prescribed category D or X drug in the second (20.3%) and third trimesters (23.1%) of pregnancy, respectively. The most common principal diagnosis during pregnancy was "disorders of menstruation and other abnormal bleeding from the female genital tract" (22% of all principal diagnoses for prescribing category D and X drugs). Conclusions: Our study found that the physicians obviously reduced the use of category D and X drugs for women after becoming aware that they were pregnant. Copyright
AB - Purpose: This study aimed to investigate the most prescribed medications and principle diagnoses for category D and X drugs during pregnancy using a population-based dataset in Taiwan. Methods: The data for the present study were sourced from the Taiwan Longitudinal Health Insurance Database 2000. We selected 14125 women who had live singleton births between 1 January 2009 and 31 December 2011. In total, 217226 prescriptions prescribed to these pregnant women were identified. Results: Of the total 217226 prescriptions, 1.1% were category D or X drugs; in the first, second, and third trimesters of pregnancy, 1.8%, 0.7%, and 0.5% of prescriptions were category D or X drugs, respectively. Progestins (15.3%) and propylthiouracil (10.7%) were the two most frequently prescribed category D or X drugs during pregnancy. In particular, progestins (20.4%) and estrogens (15.6%) were the most frequently prescribed category D or X drug in the first trimester of pregnancy. Propylthiouracil was the most prescribed category D or X drug in the second (20.3%) and third trimesters (23.1%) of pregnancy, respectively. The most common principal diagnosis during pregnancy was "disorders of menstruation and other abnormal bleeding from the female genital tract" (22% of all principal diagnoses for prescribing category D and X drugs). Conclusions: Our study found that the physicians obviously reduced the use of category D and X drugs for women after becoming aware that they were pregnant. Copyright
KW - Category D and X drugs
KW - Pharmacoepidemiology
KW - Pregnancy
KW - Prescribing behavior
UR - http://www.scopus.com/inward/record.url?scp=84911806944&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84911806944&partnerID=8YFLogxK
U2 - 10.1002/pds.3599
DO - 10.1002/pds.3599
M3 - Article
C2 - 24578346
AN - SCOPUS:84911806944
VL - 23
SP - 1029
EP - 1034
JO - Pharmacoepidemiology and Drug Safety
JF - Pharmacoepidemiology and Drug Safety
SN - 1053-8569
IS - 10
ER -