Abstract
Environmental-friendly nanocomposite hydrogels of carboxymethyl-hexanoyl chitosan (CHC), graphene oxide (GO) and cellulose nanocrystals (CNCs) were combined to produce a bio-hydrogel with great biocompatibility and antibacterial ability. The size of the GO nanosheets was about 200-500 nm, and the CNCs had a length of 100-200 nm and a width of 10-20 nm, as shown by transmission electron microscopy (TEM). X-ray photoelectron spectroscopy (XPS) was utilized for the analysis of the oxygen functional groups of GO. The homogeneous dispersion of the CHC/GO/CNC nanocomposite hydrogel showed significantly higher water absorption capacity and water retention capability. In addition, inhibition of a variety of microorganisms (gram-negative and gram-positive bacteria and fungi) by the introduction of the CHC/GO/CNC nanocomposite hydrogel demonstrated that there is a great opportunity to use it in the bio-medical field, such as for plastic masks and wound dressings.
| Original language | English |
|---|---|
| Article number | 3051 |
| Journal | Applied Sciences (Switzerland) |
| Volume | 9 |
| Issue number | 15 |
| DOIs | |
| Publication status | Published - Jan 1 2019 |
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Keywords
- Amphiphatic chitosan
- Antibacterial ability
- Cellulose nanocrystals
- Graphene oxide
- Nanocomposite hydrogel
ASJC Scopus subject areas
- Materials Science(all)
- Instrumentation
- Engineering(all)
- Process Chemistry and Technology
- Computer Science Applications
- Fluid Flow and Transfer Processes
Cite this
Preparation of amphiphilic chitosan-graphene oxide-cellulose nanocrystalline composite hydrogels and their biocompatibility and antibacterial properties. / Yang, Ming Chien; Tseng, Yi Qun; Liu, Kun Ho; Cheng, Yu Wei; Chen, Wan Tzu; Chen, Wei Ting; Hsiao, Chia Wei; Yung, Ming Chi; Hsu, Chuan Chih; Liu, Ting Yu.
In: Applied Sciences (Switzerland), Vol. 9, No. 15, 3051, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Preparation of amphiphilic chitosan-graphene oxide-cellulose nanocrystalline composite hydrogels and their biocompatibility and antibacterial properties
AU - Yang, Ming Chien
AU - Tseng, Yi Qun
AU - Liu, Kun Ho
AU - Cheng, Yu Wei
AU - Chen, Wan Tzu
AU - Chen, Wei Ting
AU - Hsiao, Chia Wei
AU - Yung, Ming Chi
AU - Hsu, Chuan Chih
AU - Liu, Ting Yu
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Environmental-friendly nanocomposite hydrogels of carboxymethyl-hexanoyl chitosan (CHC), graphene oxide (GO) and cellulose nanocrystals (CNCs) were combined to produce a bio-hydrogel with great biocompatibility and antibacterial ability. The size of the GO nanosheets was about 200-500 nm, and the CNCs had a length of 100-200 nm and a width of 10-20 nm, as shown by transmission electron microscopy (TEM). X-ray photoelectron spectroscopy (XPS) was utilized for the analysis of the oxygen functional groups of GO. The homogeneous dispersion of the CHC/GO/CNC nanocomposite hydrogel showed significantly higher water absorption capacity and water retention capability. In addition, inhibition of a variety of microorganisms (gram-negative and gram-positive bacteria and fungi) by the introduction of the CHC/GO/CNC nanocomposite hydrogel demonstrated that there is a great opportunity to use it in the bio-medical field, such as for plastic masks and wound dressings.
AB - Environmental-friendly nanocomposite hydrogels of carboxymethyl-hexanoyl chitosan (CHC), graphene oxide (GO) and cellulose nanocrystals (CNCs) were combined to produce a bio-hydrogel with great biocompatibility and antibacterial ability. The size of the GO nanosheets was about 200-500 nm, and the CNCs had a length of 100-200 nm and a width of 10-20 nm, as shown by transmission electron microscopy (TEM). X-ray photoelectron spectroscopy (XPS) was utilized for the analysis of the oxygen functional groups of GO. The homogeneous dispersion of the CHC/GO/CNC nanocomposite hydrogel showed significantly higher water absorption capacity and water retention capability. In addition, inhibition of a variety of microorganisms (gram-negative and gram-positive bacteria and fungi) by the introduction of the CHC/GO/CNC nanocomposite hydrogel demonstrated that there is a great opportunity to use it in the bio-medical field, such as for plastic masks and wound dressings.
KW - Amphiphatic chitosan
KW - Antibacterial ability
KW - Cellulose nanocrystals
KW - Graphene oxide
KW - Nanocomposite hydrogel
UR - http://www.scopus.com/inward/record.url?scp=85070687521&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85070687521&partnerID=8YFLogxK
U2 - 10.3390/app9153051
DO - 10.3390/app9153051
M3 - Article
AN - SCOPUS:85070687521
VL - 9
JO - Applied Sciences (Switzerland)
JF - Applied Sciences (Switzerland)
SN - 2076-3417
IS - 15
M1 - 3051
ER -