Prenatal ischemic stroke as a cause of neonatal seizure diagnosed by magnetic resonance diffusion-weighted imaging

Chun Shan Wu, Yong Sheng Yu, Cheng Yu Chen, Chih Chien Wang, Ann Ching Wang, Shyi Jou Chen

Research output: Contribution to journalArticle

Abstract

Perinatal ischemic stroke is a serious complication of pregnancy that may be attributed to certain specific risk factors associated with either some maternal or some infantile characteristics. While the occurrence of perinatal stroke may develop during the prepartum, intrapartum, or postpartum period, it is difficult to determine the exact time of occurrence because of obscure clinical manifestations in newborn babies. Here, we present the case of a neonate suffering from focal clonic seizure 24 hours after birth. The neonate was diagnosed as having perinatal ischemic stroke, which may have been caused by prenatal ischemic insult, as judged from the characteristic features in magnetic resonance (MR) diffusion-weighted imaging (DWI) performed a week after his birth. Finally, we strongly suggest that neonatal focal seizures be immediately investigated by MRI, especially with MR DWI. This image modality provides not only early diagnosis of perinatal ischemic stroke, but also assists to clarify the specific time (prepartum, intrapartum, or postpartum period) of the stroke's occurrence.

Original languageEnglish
Pages (from-to)135-139
Number of pages5
JournalJournal of Medical Sciences (Taiwan)
Volume28
Issue number3
Publication statusPublished - Jun 2008
Externally publishedYes

Fingerprint

Diffusion Magnetic Resonance Imaging
Seizures
Stroke
Postpartum Period
Epilepsy, Partial, Motor
Parturition
Pregnancy Complications
Psychological Stress
Early Diagnosis
Mothers

Keywords

  • Magnetic resonance diffusion-weighted imaging
  • Neonatal seizure
  • Perinatal ischemic stroke

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Prenatal ischemic stroke as a cause of neonatal seizure diagnosed by magnetic resonance diffusion-weighted imaging. / Wu, Chun Shan; Yu, Yong Sheng; Chen, Cheng Yu; Wang, Chih Chien; Wang, Ann Ching; Chen, Shyi Jou.

In: Journal of Medical Sciences (Taiwan), Vol. 28, No. 3, 06.2008, p. 135-139.

Research output: Contribution to journalArticle

Wu, Chun Shan ; Yu, Yong Sheng ; Chen, Cheng Yu ; Wang, Chih Chien ; Wang, Ann Ching ; Chen, Shyi Jou. / Prenatal ischemic stroke as a cause of neonatal seizure diagnosed by magnetic resonance diffusion-weighted imaging. In: Journal of Medical Sciences (Taiwan). 2008 ; Vol. 28, No. 3. pp. 135-139.
@article{28588d3695864b7ab98f8959faf7876d,
title = "Prenatal ischemic stroke as a cause of neonatal seizure diagnosed by magnetic resonance diffusion-weighted imaging",
abstract = "Perinatal ischemic stroke is a serious complication of pregnancy that may be attributed to certain specific risk factors associated with either some maternal or some infantile characteristics. While the occurrence of perinatal stroke may develop during the prepartum, intrapartum, or postpartum period, it is difficult to determine the exact time of occurrence because of obscure clinical manifestations in newborn babies. Here, we present the case of a neonate suffering from focal clonic seizure 24 hours after birth. The neonate was diagnosed as having perinatal ischemic stroke, which may have been caused by prenatal ischemic insult, as judged from the characteristic features in magnetic resonance (MR) diffusion-weighted imaging (DWI) performed a week after his birth. Finally, we strongly suggest that neonatal focal seizures be immediately investigated by MRI, especially with MR DWI. This image modality provides not only early diagnosis of perinatal ischemic stroke, but also assists to clarify the specific time (prepartum, intrapartum, or postpartum period) of the stroke's occurrence.",
keywords = "Magnetic resonance diffusion-weighted imaging, Neonatal seizure, Perinatal ischemic stroke",
author = "Wu, {Chun Shan} and Yu, {Yong Sheng} and Chen, {Cheng Yu} and Wang, {Chih Chien} and Wang, {Ann Ching} and Chen, {Shyi Jou}",
year = "2008",
month = "6",
language = "English",
volume = "28",
pages = "135--139",
journal = "Journal of Medical Sciences",
issn = "1011-4564",
publisher = "國防醫學院",
number = "3",

}

TY - JOUR

T1 - Prenatal ischemic stroke as a cause of neonatal seizure diagnosed by magnetic resonance diffusion-weighted imaging

AU - Wu, Chun Shan

AU - Yu, Yong Sheng

AU - Chen, Cheng Yu

AU - Wang, Chih Chien

AU - Wang, Ann Ching

AU - Chen, Shyi Jou

PY - 2008/6

Y1 - 2008/6

N2 - Perinatal ischemic stroke is a serious complication of pregnancy that may be attributed to certain specific risk factors associated with either some maternal or some infantile characteristics. While the occurrence of perinatal stroke may develop during the prepartum, intrapartum, or postpartum period, it is difficult to determine the exact time of occurrence because of obscure clinical manifestations in newborn babies. Here, we present the case of a neonate suffering from focal clonic seizure 24 hours after birth. The neonate was diagnosed as having perinatal ischemic stroke, which may have been caused by prenatal ischemic insult, as judged from the characteristic features in magnetic resonance (MR) diffusion-weighted imaging (DWI) performed a week after his birth. Finally, we strongly suggest that neonatal focal seizures be immediately investigated by MRI, especially with MR DWI. This image modality provides not only early diagnosis of perinatal ischemic stroke, but also assists to clarify the specific time (prepartum, intrapartum, or postpartum period) of the stroke's occurrence.

AB - Perinatal ischemic stroke is a serious complication of pregnancy that may be attributed to certain specific risk factors associated with either some maternal or some infantile characteristics. While the occurrence of perinatal stroke may develop during the prepartum, intrapartum, or postpartum period, it is difficult to determine the exact time of occurrence because of obscure clinical manifestations in newborn babies. Here, we present the case of a neonate suffering from focal clonic seizure 24 hours after birth. The neonate was diagnosed as having perinatal ischemic stroke, which may have been caused by prenatal ischemic insult, as judged from the characteristic features in magnetic resonance (MR) diffusion-weighted imaging (DWI) performed a week after his birth. Finally, we strongly suggest that neonatal focal seizures be immediately investigated by MRI, especially with MR DWI. This image modality provides not only early diagnosis of perinatal ischemic stroke, but also assists to clarify the specific time (prepartum, intrapartum, or postpartum period) of the stroke's occurrence.

KW - Magnetic resonance diffusion-weighted imaging

KW - Neonatal seizure

KW - Perinatal ischemic stroke

UR - http://www.scopus.com/inward/record.url?scp=47749084689&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=47749084689&partnerID=8YFLogxK

M3 - Article

VL - 28

SP - 135

EP - 139

JO - Journal of Medical Sciences

JF - Journal of Medical Sciences

SN - 1011-4564

IS - 3

ER -