Prenatal diagnosis of congenital lobar fluid overload

Pei Shan Tsai, Chih Ping Chen, Dao Chen Lin, Yu Peng Liu

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Prenatal congenital lobar fluid overload (CLFO), which was first described by Ramsay and Byron, is identical to postnatal congenital lobar overinflation. It is characterized by progressive lobar overexpansion that compresses the other adjacent lung lobes. The underlying cause can be an intrinsic cartilaginous abnormality or an extrinsic airway compression. It may be associated with cardiovascular anomalies in 12%-14% of cases and affects males more frequently than females. Most cases are diagnosed postnatally, but early antenatal diagnosis and sequential follow-up are attempted for early treatment, if clinically indicated. This article provided a thorough review of CLFO, including prenatal diagnosis and differential diagnoses, as well as comprehensive illustrations of the perinatal imaging findings of CLFO. Prenatal diagnosis of fetal lung lesions should include CLFO in the differential diagnosis and prompt investigation for associated anomalies.

Original languageEnglish
Pages (from-to)425-431
Number of pages7
JournalTaiwanese Journal of Obstetrics and Gynecology
Issue number4
Publication statusPublished - Aug 2017


  • Bronchopulmonary sequestration
  • Congenital lobar fluid overload
  • Congenital pulmonary airway malformation
  • Fetus
  • MRI

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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