Preliminary Results of Fractionated Stereotactic Radiotherapy in Patients with Advanced Hepatocellular Carcinoma

王 博民, 辛 政憲(Shin-Jeng Shiang), 鍾 娜娜, 丁 禮莉(Lai-Lei Ting), 雷 德, 林 高德

Research output: Contribution to journalArticle

Abstract

Purpose: The treatment result of advanced hepatocellular carcinoma failed from previous TACE is often unsatisfactory. To minimize the acute and late adverse effects of liver irradiation and preserve maximal normal liver tissue, fractionated stereotactic radiotherapy (R/T) is used in our institute.Materials & Methods: Twenty-three patients with advanced hepatocellular carcinoma received fractionated stereotactic radiotherapy with 55Gy in 22 fractions. All patients were assessable for side effects and response.Results: The mean regression of turner volume was 29% at 1 month after completion of R?T, 41% at 2 months and 55% at 3 months. In 17 patients with elevated serum alpha-fetoptein (AFP), 15 (88%) were found to have response in the first month after R/T, 10 (59%) had regression of more than 50% of the original level at the first month after R/T. Conclusion: For patients with advanced hepatocellular carcinoma, the fractionated stereotactic radiotherapy is a feasible modality and deserves further follow-up for outcome and toxicity.
Original languageEnglish
Pages (from-to)247-252
Number of pages6
Journal放射治療與腫瘤學
Volume6
Issue number4
DOIs
Publication statusPublished - 1999
Externally publishedYes

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Hepatocellular Carcinoma
Radiotherapy
Liver
Serum
Therapeutics

Keywords

  • 晚期肝癌
  • 多分次立體定位放射治療
  • 放射性傷害
  • Advanced hepatocellular carcinoma
  • Fractionated stereotactic radiotherapy
  • Radiation toxicity

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Preliminary Results of Fractionated Stereotactic Radiotherapy in Patients with Advanced Hepatocellular Carcinoma. / 王博民; 辛政憲(Shin-Jeng Shiang); 鍾娜娜; 丁禮莉(Lai-Lei Ting); 雷德; 林高德.

In: 放射治療與腫瘤學, Vol. 6, No. 4, 1999, p. 247-252.

Research output: Contribution to journalArticle

王博民 ; 辛政憲(Shin-Jeng Shiang) ; 鍾娜娜 ; 丁禮莉(Lai-Lei Ting) ; 雷德 ; 林高德. / Preliminary Results of Fractionated Stereotactic Radiotherapy in Patients with Advanced Hepatocellular Carcinoma. In: 放射治療與腫瘤學. 1999 ; Vol. 6, No. 4. pp. 247-252.
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AU - 鍾, 娜娜

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