Pregnancy achieved by intracytoplasmic sperm injection using cryopreserved vasal-epididymal sperm from a man with spinal cord injury

Shee Uan Chen, Jeng Yi Shieh, Yen Ho Wang, Hong Chiang Chang, Hong Nerng Ho, Yu Shih Yang

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Anejaculation and poor semen quality are two major causes of infertility in men with spinal cord injury (SCI). The poor motility of retrieved sperm usually has low fertilization potential and is thought to be unfavorable for cryopreservation. This report describes a pregnancy after intracytoplasmic sperm injection (ICSI) with cryopreserved vasal-epididymal sperm from a man with SCI and anejaculation. An attempt was made to obtain sperm through electroejaculation, but no motile sperm were found in two trials. Therefore, the subject underwent vasal aspiration. The retrieved sperm had a concentration of 26 x 106/mL and a motility of 3%. ICSI was considered to be the best choice for the couple, but the wife did not become pregnant in the first cycle of treatment. A successful pregnancy was achieved by ICSI in the second cycle using frozen-thawed sperm, supernumerary in the previous cycle, with a density of 5 x 106/mL and 1% motility. A set of healthy twins, one boy and one girl, were delivered via cesarean section at 36 weeks of gestation. Complementary to other assisted reproductive techniques, ICSI may provide men with SCI a greater opportunity to father children. The supernumerary sperm, regardless of quality, should be cryopreserved to avoid the necessity and risk of repeated assisted ejaculations and aspirations of the genital tract.

Original languageEnglish
Pages (from-to)218-221
Number of pages4
JournalArchives of Physical Medicine and Rehabilitation
Volume79
Issue number2
DOIs
Publication statusPublished - Jan 1 1998
Externally publishedYes

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Intracytoplasmic Sperm Injections
Spinal Cord Injuries
Spermatozoa
Pregnancy
Assisted Reproductive Techniques
Ejaculation
Semen Analysis
Sperm Motility
Cryopreservation
Spouses
Fertilization
Fathers
Cesarean Section
Infertility

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

Cite this

Pregnancy achieved by intracytoplasmic sperm injection using cryopreserved vasal-epididymal sperm from a man with spinal cord injury. / Chen, Shee Uan; Shieh, Jeng Yi; Wang, Yen Ho; Chang, Hong Chiang; Ho, Hong Nerng; Yang, Yu Shih.

In: Archives of Physical Medicine and Rehabilitation, Vol. 79, No. 2, 01.01.1998, p. 218-221.

Research output: Contribution to journalArticle

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