Predictors of long-term survival in hepatocellular carcinomas: A longitudinal follow-up of 108 patients with small tumors

Hung Chuen Chang, Yu Min Lin, Amy Ming Fang Yen, Sam Li Sheng Chen, Wendy Yi Ying Wu, Sherry Yueh Hsia Chiu, Jean Ching Yuan Fann, Yueh Shih Lin, Hsiu Hsi Chen, Chao Sheng Liao

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12 Citations (Scopus)

Abstract

Aim: Locoregional treatment [including percutaneous ethanol injection (PEI) therapy and transcatheter arterial chemoembolization (TACE)] provides an alternative treatment for early-diagnosed hepatocellular carcinoma (HCC). However, the long-term survival of patients after locoregional treatments remains unclear. Patients and Methods: A total of 108 patients with small HCC not indicated for surgical hepatic resection were recruited between 1991 and 1999. All patients received first treatment with PEI therapy alone or combined with TACE. We followed-up these patients until the end of 2007. Clinical attributes and biological markers in association with long-term survival were collected. Significant predictors were identified by using proportional hazards regression model. Results: The overall 1-, 3-, 5-, and 10-year cumulative survival of patients with HCC (

Original languageEnglish
Pages (from-to)5171-5178
Number of pages8
JournalAnticancer Research
Volume33
Issue number11
Publication statusPublished - Nov 2013

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Keywords

  • Aspartate aminotransferase
  • Child-Pugh score
  • Hepatocellular carcinoma
  • Percutaneous ethanol injection
  • Survival
  • Transcatheter arterial chemoembolization

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Chang, H. C., Lin, Y. M., Yen, A. M. F., Chen, S. L. S., Wu, W. Y. Y., Chiu, S. Y. H., Fann, J. C. Y., Lin, Y. S., Chen, H. H., & Liao, C. S. (2013). Predictors of long-term survival in hepatocellular carcinomas: A longitudinal follow-up of 108 patients with small tumors. Anticancer Research, 33(11), 5171-5178.