Predictors of In-Hospital Mortality in Older Adults Undergoing Hip Fracture Surgery: A Case–Control Study

Ming Hsiu Chiang, Huan Ju Lee, Yi Jie Kuo, Pei Chun Chien, Wei Chun Chang, Yueh Wu, Yu Pin Chen

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Although surgery has been proven to improve the long-term survival of older adults with hip fracture, in-hospital mortality directly resulting from repair of hip fracture is undesirable. This study aimed to identify potential prognostic factors that predict in-hospital mortality risk in elderly patients following hip fracture surgery. Materials and Methods: This case–control study comprehensively collected data from older adults with hip fracture admitted to a single medical centre. Age was selected as the cross-matching factor. Univariate and binary multivariate logistic regression models were used to estimate the odds ratios with 95% confidence intervals. A receiver operating characteristic curve was constructed to quantify the discrimination power of the model. Results: Among a total of 841 older adults who received hip fracture surgery, 17 died during hospitalisation, yielding a 2.0% in-hospital mortality rate. Using a binary multivariate logistic regression model to perform a comparison with 51 age-matched patients in survival groups, the model revealed that estimated glomerular filtration rate (eGFR) and malignant cancer history were the only 2 factors significantly correlated with in-hospital mortality. The prognostic values for the eGFR and malignant cancer history were acceptable, with areas under the curve of.76 and.67, respectively. Conclusion: The prevalence of in-hospital mortality following hip fracture is low. After adjustment for age, eGFR and malignant cancer history were identified as factors significantly correlated with in-hospital mortality. The findings of this study could assist in the early screening and detection of patients with high in-hospital mortality risks.

Original languageEnglish
JournalGeriatric Orthopaedic Surgery and Rehabilitation
Volume12
DOIs
Publication statusPublished - 2021

Keywords

  • aged
  • glomerular filtration rate
  • hip fractures
  • hospital mortality
  • postoperative period

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Rehabilitation
  • Geriatrics and Gerontology

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