Predictive factors for rebleeding in patients with peptic ulcer bleeding after multipolar electrocoagulation: A retrospective analysis

Hwai Jeng Lin, Guan Ying Tseng, Wen Ching Lo, Fa Yauh Lee, Chin Lin Perng, Full Young Chang, Shou Dong Lee

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The role of endoscopic therapy for peptic ulcer bleeding is well- documented. Nevertheless, rebleeding occurs in 10% to 30% of patients, and such patients are at high risk for death without early retreatment or definitive surgery. The aim of our study was to predict which patients would rebleed within 1 month after successful multipolar electrocoagulation of 100 patients with active peptic ulcer bleeding (spurting, oozing, or nonbleeding visible vessel). We had achieved initial hemostasis in 97 patients and carried out univariate and multivariate analyses to predict which patients would rebleed. Rebleeding occurred within I month in 17 (17.5%) patients. We correlated 20 clinical and endoscopic factors with rebleeding episodes. With univariate analysis, blood transfusion of 500 ml or more at entry (p <0.0001) and use of cimetidine (p = 0.01) were statistically significant for rebleeding. With multivariate analysis, use of omeprazole was an independent factor for preventing rebleeding (odds ratio, 7.68; 95% confidence interval, 1.642-35.929). We suggest that omeprazole may help to prevent rebleeding in patients who have had hemostasis with multipolar electrocoagulation.

Original languageEnglish
Pages (from-to)113-116
Number of pages4
JournalJournal of Clinical Gastroenterology
Volume26
Issue number2
DOIs
Publication statusPublished - Mar 1998
Externally publishedYes

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Keywords

  • Electrocoagulation
  • Hemostasis
  • Peptic ulcer

ASJC Scopus subject areas

  • Gastroenterology

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