Prediction of successful weight reduction after laparoscopic adjustable gastric banding

Yi Chih Lee, Phui Ly Liew, Wei Jei Lee, Yang Chu Lin, Chia Ko Lee, Ming Te Huang, Weu Wang, Steven C H Lin

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background/Aim: Compared with conventional pharmacological therapies, bariatric surgery has been shown to cause greater and sustained weight loss. It was aimed to evaluate weight loss in obese patients after laparoscopic adjustable gastric banding surgery using information typically available during the initial evaluation studied before bariatric surgery and genes. Methodology: 74 patients undergoing laparoscopic adjustable gastric banding (LAGB) were enrolled. Artificial Neural Network technology was used to predict weight loss. Results: We studied 74 patients consisting of 22 men and 52 women 2 years after operation. Mean age was 31.7 ± 9.1 years. 27 (36.5%) patients had successful weight reduction (excess weight loss >50%) while 47 (63.5%) did not. ANN provided predicted factors on gender, insulin, albumin and two genes: re4684846-r, rs660339-r which were associated with success. Conclusion: Artificial neural network is a better modeling technique and the predictive accuracy is higher on the basis of multiple variables related to laboratory tests. Our finding gave demonstrated result that obese patients of successful weight reduction after laparoscopic adjustable gastric banding surgery were women, having little lower insulin and albumin, and carrying GG genotype on rs4684846 and with at least one T allele on rs660339. In these cases, weight loss will give better results.

Original languageEnglish
Pages (from-to)1222-1226
Number of pages5
JournalHepato-Gastroenterology
Volume56
Issue number93
Publication statusPublished - Jul 2009

Keywords

  • Artificial neural network
  • Bariatric surgery
  • Genotype
  • Obesit
  • Weight reduction

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

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  • Cite this

    Lee, Y. C., Liew, P. L., Lee, W. J., Lin, Y. C., Lee, C. K., Huang, M. T., Wang, W., & Lin, S. C. H. (2009). Prediction of successful weight reduction after laparoscopic adjustable gastric banding. Hepato-Gastroenterology, 56(93), 1222-1226.