Predicting postoperative vomiting among orthopedic patients receiving patient-controlled epidural analgesia using SVM and LR

Hsin Yun Wu, Cihun Siyong Alex Gong, Shih Pin Lin, Kuang Yi Chang, Mei Yung Tsou, Chien Kun Ting

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Patient-controlled epidural analgesia (PCEA) has been applied to reduce postoperative pain in orthopedic surgical patients. Unfortunately, PCEA is occasionally accompanied by nausea and vomiting. The logistic regression (LR) model is widely used to predict vomiting, and recently support vector machines (SVM), a supervised machine learning method, has been used for classification and prediction. Unlike our previous work which compared Artificial Neural Networks (ANNs) with LR, this study uses a SVM-based predictive model to identify patients with high risk of vomiting during PCEA and comparing results with those derived from the LR-based model. From January to March 2007, data from 195 patients undergoing PCEA following orthopedic surgery were applied to develop two predictive models. 75% of the data were randomly selected for training, while the remainder was used for testing to validate predictive performance. The area under curve (AUC) was measured using the Receiver Operating Characteristic curve (ROC). The area under ROC curves of LR and SVM models were 0.734 and 0.929, respectively. A computer-based predictive model can be used to identify those who are at high risk for vomiting after PCEA, allowing for patient-specific therapeutic intervention or the use of alternative analgesic methods.

Original languageEnglish
Article number27041
JournalScientific Reports
Volume6
DOIs
Publication statusPublished - Jun 1 2016

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Patient-Controlled Analgesia
Postoperative Nausea and Vomiting
Epidural Analgesia
Orthopedics
Logistic Models
Vomiting
ROC Curve
Postoperative Pain
Nausea
Area Under Curve
Analgesics
Support Vector Machine

ASJC Scopus subject areas

  • General

Cite this

Predicting postoperative vomiting among orthopedic patients receiving patient-controlled epidural analgesia using SVM and LR. / Wu, Hsin Yun; Gong, Cihun Siyong Alex; Lin, Shih Pin; Chang, Kuang Yi; Tsou, Mei Yung; Ting, Chien Kun.

In: Scientific Reports, Vol. 6, 27041, 01.06.2016.

Research output: Contribution to journalArticle

Wu, Hsin Yun ; Gong, Cihun Siyong Alex ; Lin, Shih Pin ; Chang, Kuang Yi ; Tsou, Mei Yung ; Ting, Chien Kun. / Predicting postoperative vomiting among orthopedic patients receiving patient-controlled epidural analgesia using SVM and LR. In: Scientific Reports. 2016 ; Vol. 6.
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