Abstract

Unlike other deep cancers, oral squamous cell carcinoma (OSCC), which occurs in the oral cavity, is more easily monitored, and specimens for diagnosis are easier to collect. However, identifying reliable and sensitive markers for the early diagnosis and markers for identification of the recurrence of OSCC remains a challenge. This article mainly focused on reviewing recently identified potential biomarkers for a cytologic diagnosis during OSCC development. In addition, markers used in modern diagnostic technologies, including a sensitive labeling method and a photodynamic approach for cytologic diagnosis, are also described. Cytologic examinations using sensitive and specific biomarkers can improve the accuracy of the diagnosis. Hence, they can lead to appropriate treatment without delay and to the reduced recurrence of OSCC.

Original languageEnglish
Pages (from-to)60-69
Number of pages10
JournalJournal of Dental Sciences
Volume5
Issue number2
DOIs
Publication statusPublished - Jun 2010

Fingerprint

Oral Diagnosis
Squamous Cell Carcinoma
Biomarkers
Recurrence
Mouth Neoplasms
Mouth
Early Diagnosis
Technology

Keywords

  • Biomarkers
  • Cytologic diagnosis
  • Oral squamous cell carcinoma

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Potential biomarkers for the cytologic diagnosis of oral squamous cell carcinoma. / Yang, Wei Chung Vivian; Chung, Ho Ren; Wu, Jia Yo; Yi, Chen; Wang, Duen Jeng; Lee, Sheng Yang.

In: Journal of Dental Sciences, Vol. 5, No. 2, 06.2010, p. 60-69.

Research output: Contribution to journalReview article

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