Abstract
Flickering light and color patterns, reading, language, movement, decision making, eating, tapping and touching, hot water immersion and auditory stimulation can induce seizures in some epileptic patients. These are known as the 'reflex epilepsies'. The mechanism of reflex epilepsy is not clear. Recently, we performed anterior two-thirds corpus callosotomies in two reflex epilepsy patients (ages 12 and 14 years), with follow-up for more than three years. Patient 1 had Lennox-Gastaut syndrome with auditory-induced generalized atonic or tonic seizures (startle epilepsy), which decreased by 60% after callosotomy. Patient 2 had Lennox-Gastaut syndrome with somatosensory-induced generalized tonic seizures (tap epilepsy). He was seizure-free for one year immediately after callosotomy, but his seizures recurred with the same degree and frequency as before surgery. The nonsignificant postoperative seizure outcome suggests that the corpus callosum only plays a partial role in seizure generation. Our report also discusses the possible mechanisms of generation of reflex seizures.
| Original language | English |
|---|---|
| Pages (from-to) | 240-246 |
| Number of pages | 7 |
| Journal | Chinese Medical Journal (Taipei) |
| Volume | 63 |
| Issue number | 3 |
| Publication status | Published - Mar 1 2000 |
| Externally published | Yes |
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Keywords
- Callosotomy
- Corpus callosum
- Epilepsy
- Reflex epilepsy
ASJC Scopus subject areas
- Medicine(all)
Cite this
Postoperative seizure outcome after corpus callosotomy in reflex epilepsy. / Kwan, Shang Yeong; Wong, Tai-Tong; Chang, Kai Ping; Yang, Tsui Fen; Lee, Ying Chiao; Guo, Wan Yuo; Su, Ming Shung.
In: Chinese Medical Journal (Taipei), Vol. 63, No. 3, 01.03.2000, p. 240-246.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Postoperative seizure outcome after corpus callosotomy in reflex epilepsy
AU - Kwan, Shang Yeong
AU - Wong, Tai-Tong
AU - Chang, Kai Ping
AU - Yang, Tsui Fen
AU - Lee, Ying Chiao
AU - Guo, Wan Yuo
AU - Su, Ming Shung
PY - 2000/3/1
Y1 - 2000/3/1
N2 - Flickering light and color patterns, reading, language, movement, decision making, eating, tapping and touching, hot water immersion and auditory stimulation can induce seizures in some epileptic patients. These are known as the 'reflex epilepsies'. The mechanism of reflex epilepsy is not clear. Recently, we performed anterior two-thirds corpus callosotomies in two reflex epilepsy patients (ages 12 and 14 years), with follow-up for more than three years. Patient 1 had Lennox-Gastaut syndrome with auditory-induced generalized atonic or tonic seizures (startle epilepsy), which decreased by 60% after callosotomy. Patient 2 had Lennox-Gastaut syndrome with somatosensory-induced generalized tonic seizures (tap epilepsy). He was seizure-free for one year immediately after callosotomy, but his seizures recurred with the same degree and frequency as before surgery. The nonsignificant postoperative seizure outcome suggests that the corpus callosum only plays a partial role in seizure generation. Our report also discusses the possible mechanisms of generation of reflex seizures.
AB - Flickering light and color patterns, reading, language, movement, decision making, eating, tapping and touching, hot water immersion and auditory stimulation can induce seizures in some epileptic patients. These are known as the 'reflex epilepsies'. The mechanism of reflex epilepsy is not clear. Recently, we performed anterior two-thirds corpus callosotomies in two reflex epilepsy patients (ages 12 and 14 years), with follow-up for more than three years. Patient 1 had Lennox-Gastaut syndrome with auditory-induced generalized atonic or tonic seizures (startle epilepsy), which decreased by 60% after callosotomy. Patient 2 had Lennox-Gastaut syndrome with somatosensory-induced generalized tonic seizures (tap epilepsy). He was seizure-free for one year immediately after callosotomy, but his seizures recurred with the same degree and frequency as before surgery. The nonsignificant postoperative seizure outcome suggests that the corpus callosum only plays a partial role in seizure generation. Our report also discusses the possible mechanisms of generation of reflex seizures.
KW - Callosotomy
KW - Corpus callosum
KW - Epilepsy
KW - Reflex epilepsy
UR - http://www.scopus.com/inward/record.url?scp=0034075911&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034075911&partnerID=8YFLogxK
M3 - Article
C2 - 10746422
AN - SCOPUS:0034075911
VL - 63
SP - 240
EP - 246
JO - Journal of the Chinese Medical Association
JF - Journal of the Chinese Medical Association
SN - 1726-4901
IS - 3
ER -