Abstract

Background: Some studies suggested that psychological stress may be associated with the severity and duration of infectious diseases. In this populationbased study, we investigated associations between depressive disorder (DD) and pneumonia outcomes in Taiwan with a large-scale database from the National Health Insurance.

Methods: Our study defined 112,198 patients who were hospitalized with a principal diagnosis of pneumonia. We defined their admission date for treatment of pneumonia as the index date. Subsequently, we selected 2,394 patients with DD within 3 years prior to their index date and 11,970 matched patients without DD. We carried out separate conditional logistic regressions to explore the association of clinical pneumonia treatment outcome (ICU admission, use of mechanical ventilation, acute respiratory failure and in-hospital death) with previously diagnosed DD.

Results: Patients with DD had a significantly higher probability of an intensive care unit admission (18.1% vs. 12.9%; p

Original languageEnglish
Article numbere116436
JournalPLoS One
Volume9
Issue number12
DOIs
Publication statusPublished - Dec 31 2014

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Intensive care units
Depressive Disorder
pneumonia
Pneumonia
Health insurance
Logistics
health insurance
infectious diseases
National Health Programs
Taiwan
Psychological Stress
Artificial Respiration
Respiratory Insufficiency
Communicable Diseases
Intensive Care Units
death
Logistic Models
duration
Databases

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Poor clinical outcomes among pneumonia patients with depressive disorder. / Kao, Li Ting; Liu, Shih Ping; Lin, Herng Ching; Lee, Hsin Chien; Tsai, Ming Chieh; Chung, Shiu Dong.

In: PLoS One, Vol. 9, No. 12, e116436, 31.12.2014.

Research output: Contribution to journalArticle

Kao, Li Ting ; Liu, Shih Ping ; Lin, Herng Ching ; Lee, Hsin Chien ; Tsai, Ming Chieh ; Chung, Shiu Dong. / Poor clinical outcomes among pneumonia patients with depressive disorder. In: PLoS One. 2014 ; Vol. 9, No. 12.
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