Polymeric nanoparticles for therapy and imaging

Wenjie He, Hossein Hosseinkhani, Reza Mohammadinejad, Ziba Roveimiab, Dueng Yuan Hueng, Keng Liang Ou, Abraham J. Domb

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Polymeric nanoparticles and their applications have been studied over the long period. Polymeric nanoparticles have been shown to be promising carriers for drug delivery because of their potential in encapsulating drugs hence protecting them from excretion and metabolism. Different polymers have been used, and different strategies such as surface modification have been carried out to increase the retention time of nanoparticles and to increase therapeutic benefit while minimizing side effects. Here, we review aspects of polymeric nanoparticles and their application in magnetic resonance imaging technology, disease therapy, drug delivery systems, and gene transfer.

Original languageEnglish
Pages (from-to)1216-1225
Number of pages10
JournalPolymers for Advanced Technologies
Volume25
Issue number11
DOIs
Publication statusPublished - Nov 1 2014

Keywords

  • Bioimaging
  • Cancer therapy
  • Cell targeting
  • DDS
  • MRI
  • Polymeric nanoparticles

ASJC Scopus subject areas

  • Polymers and Plastics

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  • Cite this

    He, W., Hosseinkhani, H., Mohammadinejad, R., Roveimiab, Z., Hueng, D. Y., Ou, K. L., & Domb, A. J. (2014). Polymeric nanoparticles for therapy and imaging. Polymers for Advanced Technologies, 25(11), 1216-1225. https://doi.org/10.1002/pat.3381