Pituitary-testicular and pituitary-thyroid axes in spinal cord-injured males

Tien Shang Huang, Yen Ho Wang, Han-Sun Chiang, Lien Yi-Nan Lien

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Thirty spinal cord-injured (SCI) males were studied for evaluation of their pituitary-testicular and pituitary-thyroid axes using combined luteinizing hormone-releasing hormone (LHRH) and thyrotropin-releasing hormone (TRH) tests and electroejaculated semen analyses. Thirty age-matched normal male volunteers served as controls. There were four subjects with low serum triiodothyronine (T3) levels, one with elevated serum follicle-stimulating hormone (FSH) level, eight with elevated serum testosterone levels, and 11 with elevated serum prolactin levels. There were significantly elevated luteinizing hormone (LH) responses to LHRH in SCI subjects when compared with normal controls. There were 16 (53.3%) SCI subjects who had exaggerated and/or prolonged LH responses. Among them, six subjects also had elevated FSH responses. There were eight and four subjects whose thyrotropin (TSH) and prolactin responses to TRH were exaggerated, respectively. Marked impaired motility was observed in 56 electroejaculated semen samples from 16 SCI subjects. There was a significant correlation between LH and total sperm count. Our data suggest that there is a reduced central dopaminergic tone in SCI subjects.

Original languageEnglish
Pages (from-to)516-521
Number of pages6
JournalMetabolism: Clinical and Experimental
Volume42
Issue number4
DOIs
Publication statusPublished - 1993

Fingerprint

Spinal Cord
Thyroid Gland
Luteinizing Hormone
Thyrotropin-Releasing Hormone
Follicle Stimulating Hormone
Serum
Gonadotropin-Releasing Hormone
Prolactin
Semen Analysis
Sperm Count
Triiodothyronine
Thyrotropin
Semen
Testosterone
Healthy Volunteers

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Pituitary-testicular and pituitary-thyroid axes in spinal cord-injured males. / Huang, Tien Shang; Wang, Yen Ho; Chiang, Han-Sun; Yi-Nan Lien, Lien.

In: Metabolism: Clinical and Experimental, Vol. 42, No. 4, 1993, p. 516-521.

Research output: Contribution to journalArticle

Huang, Tien Shang ; Wang, Yen Ho ; Chiang, Han-Sun ; Yi-Nan Lien, Lien. / Pituitary-testicular and pituitary-thyroid axes in spinal cord-injured males. In: Metabolism: Clinical and Experimental. 1993 ; Vol. 42, No. 4. pp. 516-521.
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