Phthalate exposure pattern in breast milk within a six-month postpartum time in southern taiwan

Shen Che Hung, Ting I. Lin, Jau Ling Suen, Hsien Kuan Liu, Pei Ling Wu, Chien Yi Wu, Yu Chen S.H. Yang, San Nan Yang, Yung Ning Yang

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Di-(2-ethylhexyl) phthalate (DEHP), a common plasticizer, has been detected in breast milk in many countries; however, whether phthalate metabolite concentration and the detection rate in breast milk change postpartum is still unknown. We measured phthalate metabolite concentrations in breast milk in the first 6 months postpartum in women enrolled in the E-Da hospital from January to July 2017. A total of 56 breastfeeding mothers and 66 samples were included in this study. We analyzed the samples’ concentration of eight phthalate metabolites using liquid chromatography mass spectrometry. The concentration of mono-2-ethylhexyl phthalate (MEHP) was significantly higher in the first month, and then decreased over time. The detection rate of ono-isobutyl phthalate (MiBP) and mono-n-butyl phthalate (MBP) was low in the first month and then increased over time. Compared with a previous study published in 2011, the levels of MEHP and MiBP in breast milk were much lower in the present study, suggesting an increased awareness of the health risks of phthalate exposure after a food scandal occurred in Taiwan. This study provides information for evaluating newborns’ exposure to different kinds of phthalate through human milk in the postpartum period.

Original languageEnglish
Article number5726
JournalInternational journal of environmental research and public health
Issue number11
Publication statusPublished - Jun 1 2021


  • Breast milk
  • Di-(2-ethylhexyl) phthalate
  • Environmental endocrine disruptor

ASJC Scopus subject areas

  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


Dive into the research topics of 'Phthalate exposure pattern in breast milk within a six-month postpartum time in southern taiwan'. Together they form a unique fingerprint.

Cite this