PHILADELPHIA-CHROMOSOME-POSITIVE PRELEUKÆMIC STATE

George P. Canellos, Jacqueline Whang-Peng

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Serial chromosomal analyses were performed in an untreated patient who demonstrated little or no hæmatological disease for over 5 years before the development of overt blastic leukæmia. The Philadelphia chromosome (Ph') was present in a small percentage of marrow cells during the preleukæmic period. Hæmatological remission of the blastic leukæmia was achieved with hæmopoiesis derived from a Ph' positive cell line. The Ph' chromosome was an indicator of the preleukæmic state in the absence of other abnormalities.

Original languageEnglish
Pages (from-to)1227-1229
Number of pages3
JournalThe Lancet
Volume300
Issue number7789
DOIs
Publication statusPublished - Dec 9 1972
Externally publishedYes

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Philadelphia Chromosome
Chromosomes
Bone Marrow
Cell Line

ASJC Scopus subject areas

  • Medicine(all)

Cite this

PHILADELPHIA-CHROMOSOME-POSITIVE PRELEUKÆMIC STATE. / Canellos, George P.; Whang-Peng, Jacqueline.

In: The Lancet, Vol. 300, No. 7789, 09.12.1972, p. 1227-1229.

Research output: Contribution to journalArticle

Canellos, George P. ; Whang-Peng, Jacqueline. / PHILADELPHIA-CHROMOSOME-POSITIVE PRELEUKÆMIC STATE. In: The Lancet. 1972 ; Vol. 300, No. 7789. pp. 1227-1229.
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