Phase transformation on bone cement: Monocalcium phosphate monohydrate into calcium-deficient hydroxyapatite during setting

Shyuan Yow Chen, Shih Fu Ou, Nai Cia Teng, Chun Ming Kung, Hsien Lung Tsai, Kuo Tien Chu, Keng Liang Ou

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

This study evaluated the phase transformation of calcium phosphate cement (CPC) using a mixture of monocalcium phosphate monohydrate (MCPM) and CaCO 3 as the solid phase and either water or a sodium phosphate buffer (SPB) solution (pH=7.0) as the liquid phase. The synthetic CPC was characterized by X-ray diffraction (XRD) analysis and transmission electron microscopy (TEM). The setting reaction in the SPB solution involved three phase transformations. Firstly, MCPM and CaCO3 reacted with sodium phosphate immediately to form dicalcium phosphate dehydrate (DCPD) which continued to dissolve. Secondly, meanwhile, an intermediate amorphous calcium phosphate (ACP) was formed. Finally, ACP transformed into calcium-deficient hydroxyapatite (CDHA). In contrast, the reaction stopped at the first stage in water. Consequently, the SPB solution not only caused the dissolution of DCPD but also provided the buffering capacity to induce the conversion of the starting materials to CDHA.

Original languageEnglish
Pages (from-to)2451-2455
Number of pages5
JournalCeramics International
Volume39
Issue number3
DOIs
Publication statusPublished - Apr 2013

Fingerprint

Bone cement
Bone Cements
Durapatite
Hydroxyapatite
Calcium
Phosphates
Phase transitions
Buffers
Calcium phosphate
Cements
Sodium
Water
X ray diffraction analysis
Dissolution
Transmission electron microscopy
sodium phosphate
Liquids
amorphous calcium phosphate
anhydrous dibasic calcium phosphate
calcium phosphate

Keywords

  • Calcium phosphate cement
  • Monocalcium phosphate monohydrate
  • Phase transformation
  • Setting reaction

ASJC Scopus subject areas

  • Ceramics and Composites
  • Process Chemistry and Technology
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry

Cite this

Phase transformation on bone cement : Monocalcium phosphate monohydrate into calcium-deficient hydroxyapatite during setting. / Chen, Shyuan Yow; Ou, Shih Fu; Teng, Nai Cia; Kung, Chun Ming; Tsai, Hsien Lung; Chu, Kuo Tien; Ou, Keng Liang.

In: Ceramics International, Vol. 39, No. 3, 04.2013, p. 2451-2455.

Research output: Contribution to journalArticle

Chen, Shyuan Yow ; Ou, Shih Fu ; Teng, Nai Cia ; Kung, Chun Ming ; Tsai, Hsien Lung ; Chu, Kuo Tien ; Ou, Keng Liang. / Phase transformation on bone cement : Monocalcium phosphate monohydrate into calcium-deficient hydroxyapatite during setting. In: Ceramics International. 2013 ; Vol. 39, No. 3. pp. 2451-2455.
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