Peritoneal recurrence of gastric adenocarcinoma after curative resection

Chen Chi Lee, Su Shun Lo, Chew Wun Wu, King Han Shen, Anna F Y Li, Mao Chih Hsieh, Wing Yiu Lui

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background/Aims: Death from gastric carcinoma after curative resection is mostly due to recurrence. The most common recurrence is peritoneal dissemination, which represents 33 to 50% of total recurrence after curative gastrectomy. Since survival after peritoneal dissemination is very poor, selection of high-risk patients for further management after resection may contribute to better survival. Methodology: Based on a prospective database, a total of 1,092 patients with gastric carcinoma who underwent curative resection were included in this study. The incidence of peritoneal recurrence, disease-free interval and survival after peritoneal recurrence were determined. The clinicopathological factors including sex, age, tumor location, size, gross appearance, histological findings, depth of tumor invasion, lymph node status, tumor cell infiltration pattern were analyzed to see if there is any relationship with peritoneal dissemination. Results: The incidence of peritoneal recurrence after curative resection was 13.46%. The mean disease-free interval was 14.2 months and the survival after peritoneal recurrence was 4.9 months in average. Almost all the clinicopathological factors were related with peritoneal recurrence, but only depth of tumor invasion, gross appearance and tumor infiltration pattern are closely associated with peritoneal tumor dissemination after multivariate analyses. Conclusions: Since the prognosis after peritoneal recurrence is so poor, selection of high-risk patients for further management after gastrectomy may be based on these three factors.

Original languageEnglish
Pages (from-to)1720-1722
Number of pages3
JournalHepato-Gastroenterology
Volume50
Issue number53
Publication statusPublished - Sep 2003

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Stomach
Adenocarcinoma
Recurrence
Neoplasms
Gastrectomy
Survival
Peritoneal Diseases
Carcinoma
Sex Factors
Incidence
Disease-Free Survival
Multivariate Analysis
Lymph Nodes
Databases

Keywords

  • Gastric adenocarcinoma
  • Peritoneal recurrence
  • Risk factors

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Lee, C. C., Lo, S. S., Wu, C. W., Shen, K. H., Li, A. F. Y., Hsieh, M. C., & Lui, W. Y. (2003). Peritoneal recurrence of gastric adenocarcinoma after curative resection. Hepato-Gastroenterology, 50(53), 1720-1722.

Peritoneal recurrence of gastric adenocarcinoma after curative resection. / Lee, Chen Chi; Lo, Su Shun; Wu, Chew Wun; Shen, King Han; Li, Anna F Y; Hsieh, Mao Chih; Lui, Wing Yiu.

In: Hepato-Gastroenterology, Vol. 50, No. 53, 09.2003, p. 1720-1722.

Research output: Contribution to journalArticle

Lee, CC, Lo, SS, Wu, CW, Shen, KH, Li, AFY, Hsieh, MC & Lui, WY 2003, 'Peritoneal recurrence of gastric adenocarcinoma after curative resection', Hepato-Gastroenterology, vol. 50, no. 53, pp. 1720-1722.
Lee CC, Lo SS, Wu CW, Shen KH, Li AFY, Hsieh MC et al. Peritoneal recurrence of gastric adenocarcinoma after curative resection. Hepato-Gastroenterology. 2003 Sep;50(53):1720-1722.
Lee, Chen Chi ; Lo, Su Shun ; Wu, Chew Wun ; Shen, King Han ; Li, Anna F Y ; Hsieh, Mao Chih ; Lui, Wing Yiu. / Peritoneal recurrence of gastric adenocarcinoma after curative resection. In: Hepato-Gastroenterology. 2003 ; Vol. 50, No. 53. pp. 1720-1722.
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