Perforation of toxic megacolon in non-typhoid Salmonella enterocolitis spares young infants and is immune-mediated

C. H. Chiu, L. H. Su, C. C. He, T. H. Jaing, C. C. Luo, T. Y. Lin

Research output: Contribution to journalArticle

7 Citations (Scopus)


Intestinal perforation, a life-threatening complication of toxic megacolon (TM) following non-typhoid Salmonella infection, is relatively uncommon in infants less than 1 year of age. The situation, also found in typhoid fever, appears to be cytokine-mediated. This finding may justify immunotherapy for older children with TM associated with non-typhoid Salmonella infection in order to prevent this complication.

Original languageEnglish
Pages (from-to)410-412
Number of pages3
JournalPediatric Surgery International
Issue number5-6
Publication statusPublished - Sep 2002
Externally publishedYes



  • Intestinal perforation
  • Salmonella
  • Toxic megacolon

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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