@article{95ae04a5f8d94f2a84aa39082f09bb7c,
title = "Percutaneous endoscopic gastrostomy prior to esophagectomy for esophageal cancer–a systematic review and meta-analysis",
abstract = "Background: For resectable esophageal cancer (EC), it remains controversial whether to place percutaneous endoscopic gastrostomy (PEG) before the curative surgery to provide nutritional support during the neoadjuvant therapy. Objective: To compare surgical outcomes for patients who received preoperative PEG and those without PEG placement (No-PEG) insertion prior to surgery in a potentially operable EC. Methods: A comprehensive literature search was conducted to identify randomized and non-randomized studies comparing PEG and No-PEG groups. Results: Four retrospective studies with a total number of 1,027 patients were identified and included in this meta-analysis. The differences in anastomotic leakage, anastomotic stricture, morbidity, pulmonary complications, wound infection, and hospital stay were not statistically significant between the two groups. Operation time was significantly shorter in the PEG group. There was no PEG-related gastric conduit failure and no leak from the PEG site in the PEG group. Conclusion: We conclude preoperative PEG for resectable EC is a safe procedure with no adverse effect on the gastric tube construction and anastomosis, it can be selectively inserted for EC patients with marked weight loss and malnutrition or those at risk of developing malnutrition during neoadjuvant therapy.",
keywords = "esophagus cancer, neoadjuvant therapy, Percutaneous endoscopic gastrostomy, systematic review and meta-analysis",
author = "Fang, {Hua Chen} and Farah, {Musa Hassan} and Shiue, {Sheng Jie} and Cheng, {Sheng Wei} and Shiue, {Han Shiang} and Cheng, {Chao Ling} and Chan, {Tze Sian} and Liao, {Ai Ho} and Wu, {Ming Shun}",
note = "Funding Information: The authors thank all the staff of the Department of Internal Medicine at Wan Fang Hospital. This work was supported by Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, grant number 108-wf-eva-28 and 111-wf-eva-02 and Taipei Medical University-National Taiwan University of Science and Technology Joint Research Program, grant number TMU-NTUST-104-07 Funding Information: This work was supported by Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, and National Taiwan University of Science and Technology, Taipei, Taiwan. The authors thank all the staff of the Department of Internal Medicine at Wan Fang Hospital. This work was supported by Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, grant number 108-wf-eva-28 and 111-wf-eva-02 and Taipei Medical University-National Taiwan University of Science and Technology Joint Research Program, grant number TMU-NTUST-104-07 Funding Information: HC Fang declares the grant support by Taipei Medical University, Taipei, Taiwan, grant number 108-wf-eva-28. MS Wu declares the grant support by Taipei Medical University, Taipei, Taiwan, and National Taiwan University of Science and Technology, grant number TMU-NTUST-104-07. SJ Shiue declares the grant support by Taipei Medical University, Taipei, Taiwan, grant number 110-eva-04. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or conflict with the subject matter or materials discussed in this manuscript apart from those disclosed. Publisher Copyright: {\textcopyright} 2022 Informa UK Limited, trading as Taylor & Francis Group.",
year = "2022",
doi = "10.1080/17474124.2022.2027754",
language = "English",
volume = "16",
pages = "155--162",
journal = "Expert Review of Gastroenterology and Hepatology",
issn = "1747-4124",
publisher = "Expert Reviews Ltd.",
number = "2",
}
