Patterns of recurrence in resected non-small-cell lung cancer--emphasis on its relation to cell type and staging

C. Y. Chen, N. Y. Hsu, C. L. Chen, C. T. Lin, C. P. Hsu, P. Y. Wang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Pulmonary resection remains the most effective treatment for patients with non-small-cell lung cancer. The purpose of this study is to determine the incidence, pattern, and site of lung cancer recurrence in patients surviving resection for non-small-cell lung cancer. One hundred ninety-eight patients with post-surgical non-small-cell lung cancer were followed up from 6.5 to 0.5 years (median: 2.0 years). Recurrent cancer developed in 103 patients (52.0%). Nineteen cases had local recurrence (9.6%) and 84 (42.4%) were distant metastasis. The incidence of recurrence increased with TN status, but there was no significant difference (P = 0.451) in the overall rate of recurrent lung cancer among the various TN staging. The overall recurrent rate of non-squamous cell lung cancer was 57.4%, which was higher than 47.7% in squamous cell lung cancer. Still, it made no significant difference among the various cell types (P = 0.058). Distant metastasis occurred most commonly to the bone (22.7%), then the contralateral lung (12.6%). Curative resection with accurate staging, appropriate adjuvant therapeutic modality and continued periodic surveillance are necessary in all patients who overcome the initial carcinoma.

Original languageEnglish
Pages (from-to)169-175
Number of pages7
JournalChinese Medical Journal (Taipei)
Volume47
Issue number3
Publication statusPublished - Mar 1991
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Patterns of recurrence in resected non-small-cell lung cancer--emphasis on its relation to cell type and staging'. Together they form a unique fingerprint.

  • Cite this

    Chen, C. Y., Hsu, N. Y., Chen, C. L., Lin, C. T., Hsu, C. P., & Wang, P. Y. (1991). Patterns of recurrence in resected non-small-cell lung cancer--emphasis on its relation to cell type and staging. Chinese Medical Journal (Taipei), 47(3), 169-175.