Patterns of recurrence in resected non-small-cell lung cancer--emphasis on its relation to cell type and staging

C. Y. Chen, N. Y. Hsu, C. L. Chen, C. T. Lin, C. P. Hsu, P. Y. Wang

Research output: Contribution to journalArticle

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Abstract

Pulmonary resection remains the most effective treatment for patients with non-small-cell lung cancer. The purpose of this study is to determine the incidence, pattern, and site of lung cancer recurrence in patients surviving resection for non-small-cell lung cancer. One hundred ninety-eight patients with post-surgical non-small-cell lung cancer were followed up from 6.5 to 0.5 years (median: 2.0 years). Recurrent cancer developed in 103 patients (52.0%). Nineteen cases had local recurrence (9.6%) and 84 (42.4%) were distant metastasis. The incidence of recurrence increased with TN status, but there was no significant difference (P = 0.451) in the overall rate of recurrent lung cancer among the various TN staging. The overall recurrent rate of non-squamous cell lung cancer was 57.4%, which was higher than 47.7% in squamous cell lung cancer. Still, it made no significant difference among the various cell types (P = 0.058). Distant metastasis occurred most commonly to the bone (22.7%), then the contralateral lung (12.6%). Curative resection with accurate staging, appropriate adjuvant therapeutic modality and continued periodic surveillance are necessary in all patients who overcome the initial carcinoma.

Original languageEnglish
Pages (from-to)169-175
Number of pages7
JournalChinese Medical Journal (Taipei)
Volume47
Issue number3
Publication statusPublished - Mar 1991
Externally publishedYes

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Non-Small Cell Lung Carcinoma
Lung Neoplasms
Recurrence
Neoplasm Metastasis
Squamous Cell Neoplasms
Lung
Incidence
Carcinoma
Bone and Bones
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chen, C. Y., Hsu, N. Y., Chen, C. L., Lin, C. T., Hsu, C. P., & Wang, P. Y. (1991). Patterns of recurrence in resected non-small-cell lung cancer--emphasis on its relation to cell type and staging. Chinese Medical Journal (Taipei), 47(3), 169-175.

Patterns of recurrence in resected non-small-cell lung cancer--emphasis on its relation to cell type and staging. / Chen, C. Y.; Hsu, N. Y.; Chen, C. L.; Lin, C. T.; Hsu, C. P.; Wang, P. Y.

In: Chinese Medical Journal (Taipei), Vol. 47, No. 3, 03.1991, p. 169-175.

Research output: Contribution to journalArticle

Chen, CY, Hsu, NY, Chen, CL, Lin, CT, Hsu, CP & Wang, PY 1991, 'Patterns of recurrence in resected non-small-cell lung cancer--emphasis on its relation to cell type and staging', Chinese Medical Journal (Taipei), vol. 47, no. 3, pp. 169-175.
Chen, C. Y. ; Hsu, N. Y. ; Chen, C. L. ; Lin, C. T. ; Hsu, C. P. ; Wang, P. Y. / Patterns of recurrence in resected non-small-cell lung cancer--emphasis on its relation to cell type and staging. In: Chinese Medical Journal (Taipei). 1991 ; Vol. 47, No. 3. pp. 169-175.
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