Patterns of isolated septal hypertrophy and their clinical correlations in essential hypertension

Nen Chung Chang, Tze C. Wang, Zhi Yang Lai

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3 Citations (Scopus)


The morphological patterns and their clinical correlations in 96 essential hypertensive patients (pts) with isolated septal hypertrophy (IVSH) were studied by 2-dimensional echocardiography. Three patterns of IVSH: basal (B), diffuse (D), and midportion (M) types, were identified by parasternal long-axis image, and four patterns of hypertrophy in the left ventricular (LV) wall: diffuse except posterior wall (type I), anterolateral wall and anterior septum (type II), whole septum (type III), and anterior septum (type IV), were recognized by parasternal short-axis image. A total of 12 different types of LV hypertrophy could be classified. B + I, B + IV, and D + I types were each present in more than 10 pts. The B + IV type had the oldest mean age of 72 years (vs B + I: 63, p <0.05 and D + I: 64, p = 0.1), D + I vs B + I, p = 0.5. The D + I type had the highest mean diastolic blood pressure, 108 mmHg (vs B + I: 103, p <0.05, and B + IV: 96, p <0.001), B + I vs B + IV, p <0.01. The B + I type had the longest duration of hypertension, 24 years (vs B + IV: 15, p <0.001 and D + I: 21, p = 0.1), B + IV vs D + I, p <0.05. Seven pts (70%) of M + I type had a family history of cardiomyopathy and/or apical hypertrophy. We conclude that arterial hypertension is associated with a spectrum of isolated septal hypertrophy correlating with clinical characteristics.

Original languageEnglish
Pages (from-to)175-180
Number of pages6
JournalInternational Journal of Angiology
Issue number4
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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