Pathophysiology of the pulmonary vein as an atrial fibrillation initiator: From bench to clinic

Shih Ann Chen, Yi Jen Chen, Hung I. Yeh, Ching Tai Tai, Yao Chang Chen, Cheng I. Lin

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The basic electrophysiologic studies have proved the arrhythmogenic mechanisms of the pulmonary vein as an atrial fibrillation initiator; the mechanisms include enhanced automaticity, triggered activity, and microreentry from myocardial sleeves inside pulmonary veins. Immunohistology study has proved the conduction characteristics of pulmonary vein myocardium, and further study of ionic currents are important for understanding atrial fibrillation initiation from the pulmonary vein.

Original languageEnglish
Pages (from-to)1576-1582
Number of pages7
JournalPACE - Pacing and Clinical Electrophysiology
Volume26
Issue number7 II
Publication statusPublished - Jul 1 2003

Keywords

  • Atrial fibrillation
  • Pulmonary vein

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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