Partial Hydatidiform Mole in a Medical Abortion with the Mifepristone/Misoprostol Combination

Pui Ki Chow, Szu Yuan Chou, Chih Fen Wu, So Jung Liang, Chuan Yaw Chang, Chun Sen Hsu, Shiu Feng Huang

Research output: Contribution to journalArticle

Abstract

Objective: Gestational trophoblastic disease after an early elective medical abortion with the mifepristone/ misoprostol combination (MMC) is rare. Case Report: We report a case of a young woman who was at 6-7 weeks of gestation who requested a medical abortion. The pretreatment ultrasonogram indicated a normal pregnancy. Passage of tissue ensued after the MMC, with good recovery. Postabortal ultrasonogram on day 14 showed the presence of intracavitary content. The patient declined our suggestion of serial ultrasonographic surveillance, and she was later lost to follow- up. Fifty days after the initial treatment, she again presented to our hospital with intermittent bleeding and an increase in the blood flow signal with a low resistance index in the uterus on color Doppler ultrasonography. After curettage, she was diagnosed as having a partial hydatidiform mole; she had complete regression of beta- human chorionic gonadotropin, monitored for 1 week after the evacuation. Conclusion: Obstetricians should be aware of the possibility of a partial hydatidiform mole after a medical abortion.

Original languageEnglish
Pages (from-to)232-234
Number of pages3
JournalTaiwanese Journal of Obstetrics and Gynecology
Volume43
Issue number4
DOIs
Publication statusPublished - Dec 2004

Fingerprint

Hydatidiform Mole
Misoprostol
Mifepristone
Gestational Trophoblastic Disease
Doppler Color Ultrasonography
Pregnancy
Curettage
Lost to Follow-Up
Chorionic Gonadotropin
Uterus
Hemorrhage
Therapeutics

Keywords

  • mifepristone
  • misoprostol
  • partial mole
  • resistance index
  • ultrasonogram

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Partial Hydatidiform Mole in a Medical Abortion with the Mifepristone/Misoprostol Combination. / Chow, Pui Ki; Chou, Szu Yuan; Wu, Chih Fen; Liang, So Jung; Chang, Chuan Yaw; Hsu, Chun Sen; Huang, Shiu Feng.

In: Taiwanese Journal of Obstetrics and Gynecology, Vol. 43, No. 4, 12.2004, p. 232-234.

Research output: Contribution to journalArticle

Chow, Pui Ki ; Chou, Szu Yuan ; Wu, Chih Fen ; Liang, So Jung ; Chang, Chuan Yaw ; Hsu, Chun Sen ; Huang, Shiu Feng. / Partial Hydatidiform Mole in a Medical Abortion with the Mifepristone/Misoprostol Combination. In: Taiwanese Journal of Obstetrics and Gynecology. 2004 ; Vol. 43, No. 4. pp. 232-234.
@article{685d3c1bf35745f4b6ceb90e766e5423,
title = "Partial Hydatidiform Mole in a Medical Abortion with the Mifepristone/Misoprostol Combination",
abstract = "Objective: Gestational trophoblastic disease after an early elective medical abortion with the mifepristone/ misoprostol combination (MMC) is rare. Case Report: We report a case of a young woman who was at 6-7 weeks of gestation who requested a medical abortion. The pretreatment ultrasonogram indicated a normal pregnancy. Passage of tissue ensued after the MMC, with good recovery. Postabortal ultrasonogram on day 14 showed the presence of intracavitary content. The patient declined our suggestion of serial ultrasonographic surveillance, and she was later lost to follow- up. Fifty days after the initial treatment, she again presented to our hospital with intermittent bleeding and an increase in the blood flow signal with a low resistance index in the uterus on color Doppler ultrasonography. After curettage, she was diagnosed as having a partial hydatidiform mole; she had complete regression of beta- human chorionic gonadotropin, monitored for 1 week after the evacuation. Conclusion: Obstetricians should be aware of the possibility of a partial hydatidiform mole after a medical abortion.",
keywords = "mifepristone, misoprostol, partial mole, resistance index, ultrasonogram",
author = "Chow, {Pui Ki} and Chou, {Szu Yuan} and Wu, {Chih Fen} and Liang, {So Jung} and Chang, {Chuan Yaw} and Hsu, {Chun Sen} and Huang, {Shiu Feng}",
year = "2004",
month = "12",
doi = "10.1016/S1028-4559(09)60094-2",
language = "English",
volume = "43",
pages = "232--234",
journal = "Taiwanese Journal of Obstetrics and Gynecology",
issn = "1028-4559",
publisher = "臺灣婦產科醫學會",
number = "4",

}

TY - JOUR

T1 - Partial Hydatidiform Mole in a Medical Abortion with the Mifepristone/Misoprostol Combination

AU - Chow, Pui Ki

AU - Chou, Szu Yuan

AU - Wu, Chih Fen

AU - Liang, So Jung

AU - Chang, Chuan Yaw

AU - Hsu, Chun Sen

AU - Huang, Shiu Feng

PY - 2004/12

Y1 - 2004/12

N2 - Objective: Gestational trophoblastic disease after an early elective medical abortion with the mifepristone/ misoprostol combination (MMC) is rare. Case Report: We report a case of a young woman who was at 6-7 weeks of gestation who requested a medical abortion. The pretreatment ultrasonogram indicated a normal pregnancy. Passage of tissue ensued after the MMC, with good recovery. Postabortal ultrasonogram on day 14 showed the presence of intracavitary content. The patient declined our suggestion of serial ultrasonographic surveillance, and she was later lost to follow- up. Fifty days after the initial treatment, she again presented to our hospital with intermittent bleeding and an increase in the blood flow signal with a low resistance index in the uterus on color Doppler ultrasonography. After curettage, she was diagnosed as having a partial hydatidiform mole; she had complete regression of beta- human chorionic gonadotropin, monitored for 1 week after the evacuation. Conclusion: Obstetricians should be aware of the possibility of a partial hydatidiform mole after a medical abortion.

AB - Objective: Gestational trophoblastic disease after an early elective medical abortion with the mifepristone/ misoprostol combination (MMC) is rare. Case Report: We report a case of a young woman who was at 6-7 weeks of gestation who requested a medical abortion. The pretreatment ultrasonogram indicated a normal pregnancy. Passage of tissue ensued after the MMC, with good recovery. Postabortal ultrasonogram on day 14 showed the presence of intracavitary content. The patient declined our suggestion of serial ultrasonographic surveillance, and she was later lost to follow- up. Fifty days after the initial treatment, she again presented to our hospital with intermittent bleeding and an increase in the blood flow signal with a low resistance index in the uterus on color Doppler ultrasonography. After curettage, she was diagnosed as having a partial hydatidiform mole; she had complete regression of beta- human chorionic gonadotropin, monitored for 1 week after the evacuation. Conclusion: Obstetricians should be aware of the possibility of a partial hydatidiform mole after a medical abortion.

KW - mifepristone

KW - misoprostol

KW - partial mole

KW - resistance index

KW - ultrasonogram

UR - http://www.scopus.com/inward/record.url?scp=67651102741&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67651102741&partnerID=8YFLogxK

U2 - 10.1016/S1028-4559(09)60094-2

DO - 10.1016/S1028-4559(09)60094-2

M3 - Article

VL - 43

SP - 232

EP - 234

JO - Taiwanese Journal of Obstetrics and Gynecology

JF - Taiwanese Journal of Obstetrics and Gynecology

SN - 1028-4559

IS - 4

ER -