Parenteral glutamine supplement has synergic effects in minimally invasive surgery of subtotal gastrectomy patients

Chien Chia Chen, Tung Cheng Chang, Ming Yang Wang, Ming Hsun Wu, Ming Tsan Lin

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background/Aims: Exogenous glutamine supplement is known to improve morbidity and mortality of critically-ill patients. This study was conducted to elucidate the role of glutamine in minimally invasive surgery. Methodology: We retrospectively reviewed subtotal gastrectomy patients in National Taiwan University Hospital from Dec 2005 to Dec 2008. The patients were divided into three groups. Group 1 underwent subtotal gastrectomy by laparotomy without glutamine supplement, group 2 underwent subtotal gastrectomy by laparotomy with glutamine supplement and group 3 underwent gasless laparoscopy-assisted subtotal gastrectomy with parenteral glutamine supplement. Results: There were 155 patients in total; 85 patients in group 1, 17 in group 2 and 53 in group 3. The mean flatus days after operation are 3.6, 3.1 and 2.8 for groups 1, 2 and 3, respectively (p=0.001). Oral intake after operation was commenced after 6.7, 5.0 and 4.7 days (p=0.006). The body temperature had borderline differences between groups 3 and 1. There were significant differences in postoperative systemic responses including heart rates (p

Original languageEnglish
Pages (from-to)1776-1779
Number of pages4
JournalHepato-Gastroenterology
Volume59
Issue number118
DOIs
Publication statusPublished - Sep 2012
Externally publishedYes

Fingerprint

Minimally Invasive Surgical Procedures
Gastrectomy
Glutamine
Laparotomy
Flatulence
Body Temperature
Taiwan
Critical Illness
Laparoscopy
Heart Rate
Morbidity
Mortality

Keywords

  • Gastrectomy
  • Gastric cancer
  • Glutamine
  • Minimally invasive surgery
  • Perioperative care

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

Parenteral glutamine supplement has synergic effects in minimally invasive surgery of subtotal gastrectomy patients. / Chen, Chien Chia; Chang, Tung Cheng; Wang, Ming Yang; Wu, Ming Hsun; Lin, Ming Tsan.

In: Hepato-Gastroenterology, Vol. 59, No. 118, 09.2012, p. 1776-1779.

Research output: Contribution to journalArticle

Chen, Chien Chia ; Chang, Tung Cheng ; Wang, Ming Yang ; Wu, Ming Hsun ; Lin, Ming Tsan. / Parenteral glutamine supplement has synergic effects in minimally invasive surgery of subtotal gastrectomy patients. In: Hepato-Gastroenterology. 2012 ; Vol. 59, No. 118. pp. 1776-1779.
@article{ceb98610fd404d3d9090d402dea9f274,
title = "Parenteral glutamine supplement has synergic effects in minimally invasive surgery of subtotal gastrectomy patients",
abstract = "Background/Aims: Exogenous glutamine supplement is known to improve morbidity and mortality of critically-ill patients. This study was conducted to elucidate the role of glutamine in minimally invasive surgery. Methodology: We retrospectively reviewed subtotal gastrectomy patients in National Taiwan University Hospital from Dec 2005 to Dec 2008. The patients were divided into three groups. Group 1 underwent subtotal gastrectomy by laparotomy without glutamine supplement, group 2 underwent subtotal gastrectomy by laparotomy with glutamine supplement and group 3 underwent gasless laparoscopy-assisted subtotal gastrectomy with parenteral glutamine supplement. Results: There were 155 patients in total; 85 patients in group 1, 17 in group 2 and 53 in group 3. The mean flatus days after operation are 3.6, 3.1 and 2.8 for groups 1, 2 and 3, respectively (p=0.001). Oral intake after operation was commenced after 6.7, 5.0 and 4.7 days (p=0.006). The body temperature had borderline differences between groups 3 and 1. There were significant differences in postoperative systemic responses including heart rates (p",
keywords = "Gastrectomy, Gastric cancer, Glutamine, Minimally invasive surgery, Perioperative care",
author = "Chen, {Chien Chia} and Chang, {Tung Cheng} and Wang, {Ming Yang} and Wu, {Ming Hsun} and Lin, {Ming Tsan}",
year = "2012",
month = "9",
doi = "10.5754/hge10270",
language = "English",
volume = "59",
pages = "1776--1779",
journal = "Acta hepato-splenologica",
issn = "0172-6390",
publisher = "H.G.E. Update Medical Publishing Ltd.",
number = "118",

}

TY - JOUR

T1 - Parenteral glutamine supplement has synergic effects in minimally invasive surgery of subtotal gastrectomy patients

AU - Chen, Chien Chia

AU - Chang, Tung Cheng

AU - Wang, Ming Yang

AU - Wu, Ming Hsun

AU - Lin, Ming Tsan

PY - 2012/9

Y1 - 2012/9

N2 - Background/Aims: Exogenous glutamine supplement is known to improve morbidity and mortality of critically-ill patients. This study was conducted to elucidate the role of glutamine in minimally invasive surgery. Methodology: We retrospectively reviewed subtotal gastrectomy patients in National Taiwan University Hospital from Dec 2005 to Dec 2008. The patients were divided into three groups. Group 1 underwent subtotal gastrectomy by laparotomy without glutamine supplement, group 2 underwent subtotal gastrectomy by laparotomy with glutamine supplement and group 3 underwent gasless laparoscopy-assisted subtotal gastrectomy with parenteral glutamine supplement. Results: There were 155 patients in total; 85 patients in group 1, 17 in group 2 and 53 in group 3. The mean flatus days after operation are 3.6, 3.1 and 2.8 for groups 1, 2 and 3, respectively (p=0.001). Oral intake after operation was commenced after 6.7, 5.0 and 4.7 days (p=0.006). The body temperature had borderline differences between groups 3 and 1. There were significant differences in postoperative systemic responses including heart rates (p

AB - Background/Aims: Exogenous glutamine supplement is known to improve morbidity and mortality of critically-ill patients. This study was conducted to elucidate the role of glutamine in minimally invasive surgery. Methodology: We retrospectively reviewed subtotal gastrectomy patients in National Taiwan University Hospital from Dec 2005 to Dec 2008. The patients were divided into three groups. Group 1 underwent subtotal gastrectomy by laparotomy without glutamine supplement, group 2 underwent subtotal gastrectomy by laparotomy with glutamine supplement and group 3 underwent gasless laparoscopy-assisted subtotal gastrectomy with parenteral glutamine supplement. Results: There were 155 patients in total; 85 patients in group 1, 17 in group 2 and 53 in group 3. The mean flatus days after operation are 3.6, 3.1 and 2.8 for groups 1, 2 and 3, respectively (p=0.001). Oral intake after operation was commenced after 6.7, 5.0 and 4.7 days (p=0.006). The body temperature had borderline differences between groups 3 and 1. There were significant differences in postoperative systemic responses including heart rates (p

KW - Gastrectomy

KW - Gastric cancer

KW - Glutamine

KW - Minimally invasive surgery

KW - Perioperative care

UR - http://www.scopus.com/inward/record.url?scp=84867725866&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84867725866&partnerID=8YFLogxK

U2 - 10.5754/hge10270

DO - 10.5754/hge10270

M3 - Article

C2 - 22819900

AN - SCOPUS:84867725866

VL - 59

SP - 1776

EP - 1779

JO - Acta hepato-splenologica

JF - Acta hepato-splenologica

SN - 0172-6390

IS - 118

ER -