Parenteral glutamine supplement has synergic effects in minimally invasive surgery of subtotal gastrectomy patients

Chien Chia Chen, Tung Cheng Chang, Ming Yang Wang, Ming Hsun Wu, Ming Tsan Lin

Research output: Contribution to journalArticle

2 Citations (Scopus)


Background/Aims: Exogenous glutamine supplement is known to improve morbidity and mortality of critically-ill patients. This study was conducted to elucidate the role of glutamine in minimally invasive surgery. Methodology: We retrospectively reviewed subtotal gastrectomy patients in National Taiwan University Hospital from Dec 2005 to Dec 2008. The patients were divided into three groups. Group 1 underwent subtotal gastrectomy by laparotomy without glutamine supplement, group 2 underwent subtotal gastrectomy by laparotomy with glutamine supplement and group 3 underwent gasless laparoscopy-assisted subtotal gastrectomy with parenteral glutamine supplement. Results: There were 155 patients in total; 85 patients in group 1, 17 in group 2 and 53 in group 3. The mean flatus days after operation are 3.6, 3.1 and 2.8 for groups 1, 2 and 3, respectively (p=0.001). Oral intake after operation was commenced after 6.7, 5.0 and 4.7 days (p=0.006). The body temperature had borderline differences between groups 3 and 1. There were significant differences in postoperative systemic responses including heart rates (p

Original languageEnglish
Pages (from-to)1776-1779
Number of pages4
Issue number118
Publication statusPublished - Sep 2012
Externally publishedYes



  • Gastrectomy
  • Gastric cancer
  • Glutamine
  • Minimally invasive surgery
  • Perioperative care

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

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