Parental smoking and childhood obesity

Higher effect estimates for maternal smoking in pregnancy compared with paternal smoking-a meta-analysis

Christina Riedel, Katharina Schönberger, Seungmi Yang, Gibby Koshy, Yang Ching Chen, Bamini Gopinath, Stephanie Ziebarth, Rüdiger von Kries

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Background: Some studies reported similar effect estimates for the impact of maternal smoking in pregnancy and paternal smoking on childhood obesity, whereas others suggested higher effects for maternal smoking. We performed a meta-analysis to compare the effect of in utero exposure to maternal smoking and that of paternal or household smoking exposure in utero or after birth with mutual adjustment. Methods: Meta-analysis of observational studies identified in MEDLINE, EMBASE and Web of Knowledge published in 1900-2013. Study inclusion criterion was assessment of the association of maternal smoking during pregnancy and paternal or household smoking (anyone living in the household who smokes) at any time with childhood overweight and obesity. The analyses were based on all studies with mutually adjusted effect estimates for maternal and paternal/household smoking applying a random-effects model. Results: Data for 109 838 mother/child pairs were reported in 12 studies. The pooled odds ratios (ORs) for overweight 1.33 [95% confidence interval (CI) 1.23;1.44] (n=6, I2=0.00%) and obesity 1.60 (95% CI 1.37;1.88) (n=4, I2=32.47%) for maternal smoking during pregnancy were higher than for paternal smoking: 1.07 (95% CI 1.00;1.16) (n=6, I2=41.34%) and 1.23 (95% CI 1.10;1.38) (n=4, I2=14.61%), respectively. Similar estimates with widely overlapping confidence limits were found for maternal smoking during pregnancy and childhood overweight and obesity: 1.35 (95% CI 1.20;1.51) (n=3,I2=0.00%) and 1.28 (95% CI 1.07;1.54) (n=3, I2=0.00%) compared with household smoking 1.22 (95% CI 1.06;1.39) (n=3, I2=72.14%) and 1.31 (95% CI 1.15;1.50)] (n=3, I2=0.00%). Conclusions: Higher effect estimates for maternal smoking in pregnancy compared with paternal smoking in mutually adjusted models may suggest a direct intrauterine effect.

Original languageEnglish
Article numberdyu150
Pages (from-to)1593-1606
Number of pages14
JournalInternational Journal of Epidemiology
Volume43
Issue number5
DOIs
Publication statusPublished - Jan 1 2014
Externally publishedYes

Fingerprint

Pediatric Obesity
Meta-Analysis
Smoking
Mothers
Pregnancy
Confidence Intervals
Social Adjustment
Maternal Exposure
MEDLINE
Smoke
Observational Studies

Keywords

  • Household smoking
  • Maternal smoking
  • Meta-analysis
  • Obesity
  • Overweight
  • Paternal smoking

ASJC Scopus subject areas

  • Epidemiology
  • Medicine(all)

Cite this

Parental smoking and childhood obesity : Higher effect estimates for maternal smoking in pregnancy compared with paternal smoking-a meta-analysis. / Riedel, Christina; Schönberger, Katharina; Yang, Seungmi; Koshy, Gibby; Chen, Yang Ching; Gopinath, Bamini; Ziebarth, Stephanie; von Kries, Rüdiger.

In: International Journal of Epidemiology, Vol. 43, No. 5, dyu150, 01.01.2014, p. 1593-1606.

Research output: Contribution to journalArticle

Riedel, Christina ; Schönberger, Katharina ; Yang, Seungmi ; Koshy, Gibby ; Chen, Yang Ching ; Gopinath, Bamini ; Ziebarth, Stephanie ; von Kries, Rüdiger. / Parental smoking and childhood obesity : Higher effect estimates for maternal smoking in pregnancy compared with paternal smoking-a meta-analysis. In: International Journal of Epidemiology. 2014 ; Vol. 43, No. 5. pp. 1593-1606.
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abstract = "Background: Some studies reported similar effect estimates for the impact of maternal smoking in pregnancy and paternal smoking on childhood obesity, whereas others suggested higher effects for maternal smoking. We performed a meta-analysis to compare the effect of in utero exposure to maternal smoking and that of paternal or household smoking exposure in utero or after birth with mutual adjustment. Methods: Meta-analysis of observational studies identified in MEDLINE, EMBASE and Web of Knowledge published in 1900-2013. Study inclusion criterion was assessment of the association of maternal smoking during pregnancy and paternal or household smoking (anyone living in the household who smokes) at any time with childhood overweight and obesity. The analyses were based on all studies with mutually adjusted effect estimates for maternal and paternal/household smoking applying a random-effects model. Results: Data for 109 838 mother/child pairs were reported in 12 studies. The pooled odds ratios (ORs) for overweight 1.33 [95{\%} confidence interval (CI) 1.23;1.44] (n=6, I2=0.00{\%}) and obesity 1.60 (95{\%} CI 1.37;1.88) (n=4, I2=32.47{\%}) for maternal smoking during pregnancy were higher than for paternal smoking: 1.07 (95{\%} CI 1.00;1.16) (n=6, I2=41.34{\%}) and 1.23 (95{\%} CI 1.10;1.38) (n=4, I2=14.61{\%}), respectively. Similar estimates with widely overlapping confidence limits were found for maternal smoking during pregnancy and childhood overweight and obesity: 1.35 (95{\%} CI 1.20;1.51) (n=3,I2=0.00{\%}) and 1.28 (95{\%} CI 1.07;1.54) (n=3, I2=0.00{\%}) compared with household smoking 1.22 (95{\%} CI 1.06;1.39) (n=3, I2=72.14{\%}) and 1.31 (95{\%} CI 1.15;1.50)] (n=3, I2=0.00{\%}). Conclusions: Higher effect estimates for maternal smoking in pregnancy compared with paternal smoking in mutually adjusted models may suggest a direct intrauterine effect.",
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T2 - Higher effect estimates for maternal smoking in pregnancy compared with paternal smoking-a meta-analysis

AU - Riedel, Christina

AU - Schönberger, Katharina

AU - Yang, Seungmi

AU - Koshy, Gibby

AU - Chen, Yang Ching

AU - Gopinath, Bamini

AU - Ziebarth, Stephanie

AU - von Kries, Rüdiger

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N2 - Background: Some studies reported similar effect estimates for the impact of maternal smoking in pregnancy and paternal smoking on childhood obesity, whereas others suggested higher effects for maternal smoking. We performed a meta-analysis to compare the effect of in utero exposure to maternal smoking and that of paternal or household smoking exposure in utero or after birth with mutual adjustment. Methods: Meta-analysis of observational studies identified in MEDLINE, EMBASE and Web of Knowledge published in 1900-2013. Study inclusion criterion was assessment of the association of maternal smoking during pregnancy and paternal or household smoking (anyone living in the household who smokes) at any time with childhood overweight and obesity. The analyses were based on all studies with mutually adjusted effect estimates for maternal and paternal/household smoking applying a random-effects model. Results: Data for 109 838 mother/child pairs were reported in 12 studies. The pooled odds ratios (ORs) for overweight 1.33 [95% confidence interval (CI) 1.23;1.44] (n=6, I2=0.00%) and obesity 1.60 (95% CI 1.37;1.88) (n=4, I2=32.47%) for maternal smoking during pregnancy were higher than for paternal smoking: 1.07 (95% CI 1.00;1.16) (n=6, I2=41.34%) and 1.23 (95% CI 1.10;1.38) (n=4, I2=14.61%), respectively. Similar estimates with widely overlapping confidence limits were found for maternal smoking during pregnancy and childhood overweight and obesity: 1.35 (95% CI 1.20;1.51) (n=3,I2=0.00%) and 1.28 (95% CI 1.07;1.54) (n=3, I2=0.00%) compared with household smoking 1.22 (95% CI 1.06;1.39) (n=3, I2=72.14%) and 1.31 (95% CI 1.15;1.50)] (n=3, I2=0.00%). Conclusions: Higher effect estimates for maternal smoking in pregnancy compared with paternal smoking in mutually adjusted models may suggest a direct intrauterine effect.

AB - Background: Some studies reported similar effect estimates for the impact of maternal smoking in pregnancy and paternal smoking on childhood obesity, whereas others suggested higher effects for maternal smoking. We performed a meta-analysis to compare the effect of in utero exposure to maternal smoking and that of paternal or household smoking exposure in utero or after birth with mutual adjustment. Methods: Meta-analysis of observational studies identified in MEDLINE, EMBASE and Web of Knowledge published in 1900-2013. Study inclusion criterion was assessment of the association of maternal smoking during pregnancy and paternal or household smoking (anyone living in the household who smokes) at any time with childhood overweight and obesity. The analyses were based on all studies with mutually adjusted effect estimates for maternal and paternal/household smoking applying a random-effects model. Results: Data for 109 838 mother/child pairs were reported in 12 studies. The pooled odds ratios (ORs) for overweight 1.33 [95% confidence interval (CI) 1.23;1.44] (n=6, I2=0.00%) and obesity 1.60 (95% CI 1.37;1.88) (n=4, I2=32.47%) for maternal smoking during pregnancy were higher than for paternal smoking: 1.07 (95% CI 1.00;1.16) (n=6, I2=41.34%) and 1.23 (95% CI 1.10;1.38) (n=4, I2=14.61%), respectively. Similar estimates with widely overlapping confidence limits were found for maternal smoking during pregnancy and childhood overweight and obesity: 1.35 (95% CI 1.20;1.51) (n=3,I2=0.00%) and 1.28 (95% CI 1.07;1.54) (n=3, I2=0.00%) compared with household smoking 1.22 (95% CI 1.06;1.39) (n=3, I2=72.14%) and 1.31 (95% CI 1.15;1.50)] (n=3, I2=0.00%). Conclusions: Higher effect estimates for maternal smoking in pregnancy compared with paternal smoking in mutually adjusted models may suggest a direct intrauterine effect.

KW - Household smoking

KW - Maternal smoking

KW - Meta-analysis

KW - Obesity

KW - Overweight

KW - Paternal smoking

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