Pain relief following spinal lesion treatment with stereotactic radiosurgery: Clinical experience in 65 cases

Shih Wei Hsu, Hsing Lung Chao, Kuen Tze Lin, Yu Ching Chou, Cheng Hsiang Lo, Shih Yu Lee, Wen Yen Huang, Chun Shu Lin, Chien Min Lin, Chao Yueh Fan, Da Tong Ju

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This study determines the pain-reducing effect of CyberKnife radiosurgery in the treatment of spinal lesions. Materials and Methods: We evaluated the clinical outcomes of patients treated with CyberKnife radiosurgery for spinal lesions in 65 patients with 76 spinal lesions at Tri-Service General Hospital, Taipei, Taiwan, from July 2007 to May 2013. Pre- and post-treatment visual analog scale (VAS) scores for pain were obtained. Results: In the benign cases, 12 patients had a pretreatment VAS score of 7 (46.2%); 12 patients, 8 (46.2%); and 2 patients, 9 (7.7%). For the posttreatment VAS scores, 10 patients had a score of 1 (38.4%); 15 patients, 2 (57.7%); and 1 patient, 4 (3.8%). In the malignant cases, 2 patients had a pretreatment VAS score of 8 (28.6%); 3 patients, 9 (42.9%); and 2 patients, 10 (28.6%). For the posttreatment VAS scores, 1 patient had a score of 2 (14.3%) and 6 patients had a score of 3 (85.7%). In the metastatic cases, 15 patients had a pretreatment VAS score of 8 (46.9%); 7 patients, 9 (21.9%); and 10 patients, 10 (31.3%). For the posttreatment VAS scores, 3 patients had a score of 1 (9.4%); 11 patients, 2 (34.4%); 16 patients, 3 (50%); and 2 patients, 4 (6.3%). Wilcoxon signed-rank tests to compare the pre- and post-treatment VAS scores in each patient group showed significant decreases in all groups (P <0.05 for all comparisons). Conclusions: Collectively, these results show that significant pain relief without obvious adverse effects can be achieved when treating spinal lesions using stereotactic radiosurgery.

Original languageEnglish
Pages (from-to)162-168
Number of pages7
JournalJournal of Medical Sciences (Taiwan)
Volume35
Issue number4
DOIs
Publication statusPublished - Aug 28 2015

Fingerprint

Radiosurgery
Pain
Visual Analog Scale
Therapeutics

Keywords

  • CyberKnife
  • Lesion
  • Pain reduction
  • Spine
  • Stereotactic radiosurgery

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Pain relief following spinal lesion treatment with stereotactic radiosurgery : Clinical experience in 65 cases. / Hsu, Shih Wei; Chao, Hsing Lung; Lin, Kuen Tze; Chou, Yu Ching; Lo, Cheng Hsiang; Lee, Shih Yu; Huang, Wen Yen; Lin, Chun Shu; Lin, Chien Min; Fan, Chao Yueh; Ju, Da Tong.

In: Journal of Medical Sciences (Taiwan), Vol. 35, No. 4, 28.08.2015, p. 162-168.

Research output: Contribution to journalArticle

Hsu, SW, Chao, HL, Lin, KT, Chou, YC, Lo, CH, Lee, SY, Huang, WY, Lin, CS, Lin, CM, Fan, CY & Ju, DT 2015, 'Pain relief following spinal lesion treatment with stereotactic radiosurgery: Clinical experience in 65 cases', Journal of Medical Sciences (Taiwan), vol. 35, no. 4, pp. 162-168. https://doi.org/10.4103/1011-4564.163824
Hsu, Shih Wei ; Chao, Hsing Lung ; Lin, Kuen Tze ; Chou, Yu Ching ; Lo, Cheng Hsiang ; Lee, Shih Yu ; Huang, Wen Yen ; Lin, Chun Shu ; Lin, Chien Min ; Fan, Chao Yueh ; Ju, Da Tong. / Pain relief following spinal lesion treatment with stereotactic radiosurgery : Clinical experience in 65 cases. In: Journal of Medical Sciences (Taiwan). 2015 ; Vol. 35, No. 4. pp. 162-168.
@article{262c4025930b40c6a99f7563901009a7,
title = "Pain relief following spinal lesion treatment with stereotactic radiosurgery: Clinical experience in 65 cases",
abstract = "This study determines the pain-reducing effect of CyberKnife radiosurgery in the treatment of spinal lesions. Materials and Methods: We evaluated the clinical outcomes of patients treated with CyberKnife radiosurgery for spinal lesions in 65 patients with 76 spinal lesions at Tri-Service General Hospital, Taipei, Taiwan, from July 2007 to May 2013. Pre- and post-treatment visual analog scale (VAS) scores for pain were obtained. Results: In the benign cases, 12 patients had a pretreatment VAS score of 7 (46.2{\%}); 12 patients, 8 (46.2{\%}); and 2 patients, 9 (7.7{\%}). For the posttreatment VAS scores, 10 patients had a score of 1 (38.4{\%}); 15 patients, 2 (57.7{\%}); and 1 patient, 4 (3.8{\%}). In the malignant cases, 2 patients had a pretreatment VAS score of 8 (28.6{\%}); 3 patients, 9 (42.9{\%}); and 2 patients, 10 (28.6{\%}). For the posttreatment VAS scores, 1 patient had a score of 2 (14.3{\%}) and 6 patients had a score of 3 (85.7{\%}). In the metastatic cases, 15 patients had a pretreatment VAS score of 8 (46.9{\%}); 7 patients, 9 (21.9{\%}); and 10 patients, 10 (31.3{\%}). For the posttreatment VAS scores, 3 patients had a score of 1 (9.4{\%}); 11 patients, 2 (34.4{\%}); 16 patients, 3 (50{\%}); and 2 patients, 4 (6.3{\%}). Wilcoxon signed-rank tests to compare the pre- and post-treatment VAS scores in each patient group showed significant decreases in all groups (P <0.05 for all comparisons). Conclusions: Collectively, these results show that significant pain relief without obvious adverse effects can be achieved when treating spinal lesions using stereotactic radiosurgery.",
keywords = "CyberKnife, Lesion, Pain reduction, Spine, Stereotactic radiosurgery",
author = "Hsu, {Shih Wei} and Chao, {Hsing Lung} and Lin, {Kuen Tze} and Chou, {Yu Ching} and Lo, {Cheng Hsiang} and Lee, {Shih Yu} and Huang, {Wen Yen} and Lin, {Chun Shu} and Lin, {Chien Min} and Fan, {Chao Yueh} and Ju, {Da Tong}",
year = "2015",
month = "8",
day = "28",
doi = "10.4103/1011-4564.163824",
language = "English",
volume = "35",
pages = "162--168",
journal = "Journal of Medical Sciences",
issn = "1011-4564",
publisher = "國防醫學院",
number = "4",

}

TY - JOUR

T1 - Pain relief following spinal lesion treatment with stereotactic radiosurgery

T2 - Clinical experience in 65 cases

AU - Hsu, Shih Wei

AU - Chao, Hsing Lung

AU - Lin, Kuen Tze

AU - Chou, Yu Ching

AU - Lo, Cheng Hsiang

AU - Lee, Shih Yu

AU - Huang, Wen Yen

AU - Lin, Chun Shu

AU - Lin, Chien Min

AU - Fan, Chao Yueh

AU - Ju, Da Tong

PY - 2015/8/28

Y1 - 2015/8/28

N2 - This study determines the pain-reducing effect of CyberKnife radiosurgery in the treatment of spinal lesions. Materials and Methods: We evaluated the clinical outcomes of patients treated with CyberKnife radiosurgery for spinal lesions in 65 patients with 76 spinal lesions at Tri-Service General Hospital, Taipei, Taiwan, from July 2007 to May 2013. Pre- and post-treatment visual analog scale (VAS) scores for pain were obtained. Results: In the benign cases, 12 patients had a pretreatment VAS score of 7 (46.2%); 12 patients, 8 (46.2%); and 2 patients, 9 (7.7%). For the posttreatment VAS scores, 10 patients had a score of 1 (38.4%); 15 patients, 2 (57.7%); and 1 patient, 4 (3.8%). In the malignant cases, 2 patients had a pretreatment VAS score of 8 (28.6%); 3 patients, 9 (42.9%); and 2 patients, 10 (28.6%). For the posttreatment VAS scores, 1 patient had a score of 2 (14.3%) and 6 patients had a score of 3 (85.7%). In the metastatic cases, 15 patients had a pretreatment VAS score of 8 (46.9%); 7 patients, 9 (21.9%); and 10 patients, 10 (31.3%). For the posttreatment VAS scores, 3 patients had a score of 1 (9.4%); 11 patients, 2 (34.4%); 16 patients, 3 (50%); and 2 patients, 4 (6.3%). Wilcoxon signed-rank tests to compare the pre- and post-treatment VAS scores in each patient group showed significant decreases in all groups (P <0.05 for all comparisons). Conclusions: Collectively, these results show that significant pain relief without obvious adverse effects can be achieved when treating spinal lesions using stereotactic radiosurgery.

AB - This study determines the pain-reducing effect of CyberKnife radiosurgery in the treatment of spinal lesions. Materials and Methods: We evaluated the clinical outcomes of patients treated with CyberKnife radiosurgery for spinal lesions in 65 patients with 76 spinal lesions at Tri-Service General Hospital, Taipei, Taiwan, from July 2007 to May 2013. Pre- and post-treatment visual analog scale (VAS) scores for pain were obtained. Results: In the benign cases, 12 patients had a pretreatment VAS score of 7 (46.2%); 12 patients, 8 (46.2%); and 2 patients, 9 (7.7%). For the posttreatment VAS scores, 10 patients had a score of 1 (38.4%); 15 patients, 2 (57.7%); and 1 patient, 4 (3.8%). In the malignant cases, 2 patients had a pretreatment VAS score of 8 (28.6%); 3 patients, 9 (42.9%); and 2 patients, 10 (28.6%). For the posttreatment VAS scores, 1 patient had a score of 2 (14.3%) and 6 patients had a score of 3 (85.7%). In the metastatic cases, 15 patients had a pretreatment VAS score of 8 (46.9%); 7 patients, 9 (21.9%); and 10 patients, 10 (31.3%). For the posttreatment VAS scores, 3 patients had a score of 1 (9.4%); 11 patients, 2 (34.4%); 16 patients, 3 (50%); and 2 patients, 4 (6.3%). Wilcoxon signed-rank tests to compare the pre- and post-treatment VAS scores in each patient group showed significant decreases in all groups (P <0.05 for all comparisons). Conclusions: Collectively, these results show that significant pain relief without obvious adverse effects can be achieved when treating spinal lesions using stereotactic radiosurgery.

KW - CyberKnife

KW - Lesion

KW - Pain reduction

KW - Spine

KW - Stereotactic radiosurgery

UR - http://www.scopus.com/inward/record.url?scp=84940468238&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84940468238&partnerID=8YFLogxK

U2 - 10.4103/1011-4564.163824

DO - 10.4103/1011-4564.163824

M3 - Article

AN - SCOPUS:84940468238

VL - 35

SP - 162

EP - 168

JO - Journal of Medical Sciences

JF - Journal of Medical Sciences

SN - 1011-4564

IS - 4

ER -