Outcome of drug-eluting balloon angioplasty versus endarterectomy in common femoral artery occlusive disease

Tzu Ting Kuo, Po Lin Chen, Chun Yang Huang, Chiu Yang Lee, Chun Che Shih, I. Ming Chen

Research output: Contribution to journalArticle

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Abstract

Objective: Common femoral artery (CFA) occlusive disease remains a debatable site for endovascular therapy, and the outcome of drug-eluting balloon (DEB) angioplasty in treating CFA occlusive disease is largely unknown. This study compared the efficacy, safety, and short-term patency rate of DEB angioplasty and femoral endarterectomy for treatment of CFA occlusive disease. Methods: From March 2013 to June 2016, there were 100 patients with symptomatic CFA occlusive disease who were retrospectively reviewed. Forty patients were treated with DEB angioplasty and 60 were treated with femoral endarterectomy. Each patient received regular follow-up. Patency rate, ankle-brachial index, target lesion revascularization, and adverse events were assessed. Results: Technical success was 100% in all patients. The DEB group had a lower 1-year primary patency rate (75.0% vs 96.7%; P =.003), but the secondary patency rate was similar between the two groups (97.5% vs 98.3%; P = 1.000). At 2-year follow-up, the primary patency was lower in the DEB group (57.1%) than in the endarterectomy group (94.1%; P =.001), whereas the secondary patency rate had no significant difference (90.5% vs 97.1%; P = 1.000). Both groups had significant improvement in ankle-brachial index. Freedom from target lesion revascularization was lower in the DEB group both at 1 year (75.0% vs 96.7%; P =.003) and at 2 years (57.1% vs 94.1%; P =.001). There was no significant difference in the incidence of complications and adverse events. Conclusions: Femoral endarterectomy has a better primary patency rate compared with DEB angioplasty in treating CFA occlusive disease without significant increase in complications. In patients not suitable for endarterectomy, DEB angioplasty provides a similar secondary patency rate and could be considered an alternative treatment.

Original languageEnglish
Pages (from-to)141-147
Number of pages7
JournalJournal of Vascular Surgery
Volume69
Issue number1
DOIs
Publication statusPublished - Jan 1 2019
Externally publishedYes

Fingerprint

Endarterectomy
Balloon Angioplasty
Femoral Artery
Pharmaceutical Preparations
Thigh
Ankle Brachial Index
Safety
Drug Therapy
Incidence
Therapeutics

Keywords

  • Common femoral artery
  • Drug-eluting balloon
  • Endarterectomy

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

Outcome of drug-eluting balloon angioplasty versus endarterectomy in common femoral artery occlusive disease. / Kuo, Tzu Ting; Chen, Po Lin; Huang, Chun Yang; Lee, Chiu Yang; Shih, Chun Che; Chen, I. Ming.

In: Journal of Vascular Surgery, Vol. 69, No. 1, 01.01.2019, p. 141-147.

Research output: Contribution to journalArticle

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abstract = "Objective: Common femoral artery (CFA) occlusive disease remains a debatable site for endovascular therapy, and the outcome of drug-eluting balloon (DEB) angioplasty in treating CFA occlusive disease is largely unknown. This study compared the efficacy, safety, and short-term patency rate of DEB angioplasty and femoral endarterectomy for treatment of CFA occlusive disease. Methods: From March 2013 to June 2016, there were 100 patients with symptomatic CFA occlusive disease who were retrospectively reviewed. Forty patients were treated with DEB angioplasty and 60 were treated with femoral endarterectomy. Each patient received regular follow-up. Patency rate, ankle-brachial index, target lesion revascularization, and adverse events were assessed. Results: Technical success was 100{\%} in all patients. The DEB group had a lower 1-year primary patency rate (75.0{\%} vs 96.7{\%}; P =.003), but the secondary patency rate was similar between the two groups (97.5{\%} vs 98.3{\%}; P = 1.000). At 2-year follow-up, the primary patency was lower in the DEB group (57.1{\%}) than in the endarterectomy group (94.1{\%}; P =.001), whereas the secondary patency rate had no significant difference (90.5{\%} vs 97.1{\%}; P = 1.000). Both groups had significant improvement in ankle-brachial index. Freedom from target lesion revascularization was lower in the DEB group both at 1 year (75.0{\%} vs 96.7{\%}; P =.003) and at 2 years (57.1{\%} vs 94.1{\%}; P =.001). There was no significant difference in the incidence of complications and adverse events. Conclusions: Femoral endarterectomy has a better primary patency rate compared with DEB angioplasty in treating CFA occlusive disease without significant increase in complications. In patients not suitable for endarterectomy, DEB angioplasty provides a similar secondary patency rate and could be considered an alternative treatment.",
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AU - Chen, Po Lin

AU - Huang, Chun Yang

AU - Lee, Chiu Yang

AU - Shih, Chun Che

AU - Chen, I. Ming

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N2 - Objective: Common femoral artery (CFA) occlusive disease remains a debatable site for endovascular therapy, and the outcome of drug-eluting balloon (DEB) angioplasty in treating CFA occlusive disease is largely unknown. This study compared the efficacy, safety, and short-term patency rate of DEB angioplasty and femoral endarterectomy for treatment of CFA occlusive disease. Methods: From March 2013 to June 2016, there were 100 patients with symptomatic CFA occlusive disease who were retrospectively reviewed. Forty patients were treated with DEB angioplasty and 60 were treated with femoral endarterectomy. Each patient received regular follow-up. Patency rate, ankle-brachial index, target lesion revascularization, and adverse events were assessed. Results: Technical success was 100% in all patients. The DEB group had a lower 1-year primary patency rate (75.0% vs 96.7%; P =.003), but the secondary patency rate was similar between the two groups (97.5% vs 98.3%; P = 1.000). At 2-year follow-up, the primary patency was lower in the DEB group (57.1%) than in the endarterectomy group (94.1%; P =.001), whereas the secondary patency rate had no significant difference (90.5% vs 97.1%; P = 1.000). Both groups had significant improvement in ankle-brachial index. Freedom from target lesion revascularization was lower in the DEB group both at 1 year (75.0% vs 96.7%; P =.003) and at 2 years (57.1% vs 94.1%; P =.001). There was no significant difference in the incidence of complications and adverse events. Conclusions: Femoral endarterectomy has a better primary patency rate compared with DEB angioplasty in treating CFA occlusive disease without significant increase in complications. In patients not suitable for endarterectomy, DEB angioplasty provides a similar secondary patency rate and could be considered an alternative treatment.

AB - Objective: Common femoral artery (CFA) occlusive disease remains a debatable site for endovascular therapy, and the outcome of drug-eluting balloon (DEB) angioplasty in treating CFA occlusive disease is largely unknown. This study compared the efficacy, safety, and short-term patency rate of DEB angioplasty and femoral endarterectomy for treatment of CFA occlusive disease. Methods: From March 2013 to June 2016, there were 100 patients with symptomatic CFA occlusive disease who were retrospectively reviewed. Forty patients were treated with DEB angioplasty and 60 were treated with femoral endarterectomy. Each patient received regular follow-up. Patency rate, ankle-brachial index, target lesion revascularization, and adverse events were assessed. Results: Technical success was 100% in all patients. The DEB group had a lower 1-year primary patency rate (75.0% vs 96.7%; P =.003), but the secondary patency rate was similar between the two groups (97.5% vs 98.3%; P = 1.000). At 2-year follow-up, the primary patency was lower in the DEB group (57.1%) than in the endarterectomy group (94.1%; P =.001), whereas the secondary patency rate had no significant difference (90.5% vs 97.1%; P = 1.000). Both groups had significant improvement in ankle-brachial index. Freedom from target lesion revascularization was lower in the DEB group both at 1 year (75.0% vs 96.7%; P =.003) and at 2 years (57.1% vs 94.1%; P =.001). There was no significant difference in the incidence of complications and adverse events. Conclusions: Femoral endarterectomy has a better primary patency rate compared with DEB angioplasty in treating CFA occlusive disease without significant increase in complications. In patients not suitable for endarterectomy, DEB angioplasty provides a similar secondary patency rate and could be considered an alternative treatment.

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