Outbreak of aseptic meningitis among adults in southern Taiwan

Chih Hsiang Kao, S. S J Lee, Yung Ching Liu, Muh Yong Yen, Yao Shen Chen, Shue R. Wan, Hsi Hsun Lin, Wei R. Lin, Chun K. Huang, Chuen Chin

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A total of 38 adult cases of aseptic meningitis were diagnosed based on clinical manifestations as well as examination of cerebrospinal fluid at Kaohsiung Veterans General Hospital in 2001. The majority (31 cases, 82%) of cases occurred between June and August, and most (33 cases, 87%) of them aged from 18 to 35 years (median age, 25 years). The male-to-female ratio was 2.16: 1. Common clinical presentations included headache, fever, nausea or vomiting, and symptoms of common cold. On initial cerebrospinal fluid examination, white cell counts were above 500 cells/mm3 in 7 (18%) cases, and neutrophils predominated in 10 (28%) of 36 cases. The cerebrospinal fluid protein concentration was below 100 mg/dL in 29 (77%) of 38 cases, and hypoglycorrhachia (cerebrospinal fluid/serum glucose ratio 2 = 12.05, p=0.007). All patients were discharged uneventfully without receiving antibiotic therapy.

Original languageEnglish
Pages (from-to)192-196
Number of pages5
JournalJournal of Microbiology, Immunology and Infection
Volume36
Issue number3
Publication statusPublished - Sep 2003
Externally publishedYes

Fingerprint

Aseptic Meningitis
Taiwan
Disease Outbreaks
Cerebrospinal Fluid
Cerebrospinal Fluid Proteins
Veterans Hospitals
Common Cold
General Hospitals
Nausea
Vomiting
Headache
Neutrophils
Fever
Cell Count
Anti-Bacterial Agents
Glucose
Serum
Therapeutics

Keywords

  • Adult
  • Aseptic meningitis
  • Echovirus
  • Outbreak
  • Taiwan

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Immunology and Allergy
  • Microbiology (medical)

Cite this

Kao, C. H., Lee, S. S. J., Liu, Y. C., Yen, M. Y., Chen, Y. S., Wan, S. R., ... Chin, C. (2003). Outbreak of aseptic meningitis among adults in southern Taiwan. Journal of Microbiology, Immunology and Infection, 36(3), 192-196.

Outbreak of aseptic meningitis among adults in southern Taiwan. / Kao, Chih Hsiang; Lee, S. S J; Liu, Yung Ching; Yen, Muh Yong; Chen, Yao Shen; Wan, Shue R.; Lin, Hsi Hsun; Lin, Wei R.; Huang, Chun K.; Chin, Chuen.

In: Journal of Microbiology, Immunology and Infection, Vol. 36, No. 3, 09.2003, p. 192-196.

Research output: Contribution to journalArticle

Kao, CH, Lee, SSJ, Liu, YC, Yen, MY, Chen, YS, Wan, SR, Lin, HH, Lin, WR, Huang, CK & Chin, C 2003, 'Outbreak of aseptic meningitis among adults in southern Taiwan', Journal of Microbiology, Immunology and Infection, vol. 36, no. 3, pp. 192-196.
Kao, Chih Hsiang ; Lee, S. S J ; Liu, Yung Ching ; Yen, Muh Yong ; Chen, Yao Shen ; Wan, Shue R. ; Lin, Hsi Hsun ; Lin, Wei R. ; Huang, Chun K. ; Chin, Chuen. / Outbreak of aseptic meningitis among adults in southern Taiwan. In: Journal of Microbiology, Immunology and Infection. 2003 ; Vol. 36, No. 3. pp. 192-196.
@article{1e4ec0a1dc0d4561805cb5b346c7b1df,
title = "Outbreak of aseptic meningitis among adults in southern Taiwan",
abstract = "A total of 38 adult cases of aseptic meningitis were diagnosed based on clinical manifestations as well as examination of cerebrospinal fluid at Kaohsiung Veterans General Hospital in 2001. The majority (31 cases, 82{\%}) of cases occurred between June and August, and most (33 cases, 87{\%}) of them aged from 18 to 35 years (median age, 25 years). The male-to-female ratio was 2.16: 1. Common clinical presentations included headache, fever, nausea or vomiting, and symptoms of common cold. On initial cerebrospinal fluid examination, white cell counts were above 500 cells/mm3 in 7 (18{\%}) cases, and neutrophils predominated in 10 (28{\%}) of 36 cases. The cerebrospinal fluid protein concentration was below 100 mg/dL in 29 (77{\%}) of 38 cases, and hypoglycorrhachia (cerebrospinal fluid/serum glucose ratio 2 = 12.05, p=0.007). All patients were discharged uneventfully without receiving antibiotic therapy.",
keywords = "Adult, Aseptic meningitis, Echovirus, Outbreak, Taiwan",
author = "Kao, {Chih Hsiang} and Lee, {S. S J} and Liu, {Yung Ching} and Yen, {Muh Yong} and Chen, {Yao Shen} and Wan, {Shue R.} and Lin, {Hsi Hsun} and Lin, {Wei R.} and Huang, {Chun K.} and Chuen Chin",
year = "2003",
month = "9",
language = "English",
volume = "36",
pages = "192--196",
journal = "Journal of Microbiology, Immunology and Infection",
issn = "0253-2662",
publisher = "Elsevier Taiwan LLC",
number = "3",

}

TY - JOUR

T1 - Outbreak of aseptic meningitis among adults in southern Taiwan

AU - Kao, Chih Hsiang

AU - Lee, S. S J

AU - Liu, Yung Ching

AU - Yen, Muh Yong

AU - Chen, Yao Shen

AU - Wan, Shue R.

AU - Lin, Hsi Hsun

AU - Lin, Wei R.

AU - Huang, Chun K.

AU - Chin, Chuen

PY - 2003/9

Y1 - 2003/9

N2 - A total of 38 adult cases of aseptic meningitis were diagnosed based on clinical manifestations as well as examination of cerebrospinal fluid at Kaohsiung Veterans General Hospital in 2001. The majority (31 cases, 82%) of cases occurred between June and August, and most (33 cases, 87%) of them aged from 18 to 35 years (median age, 25 years). The male-to-female ratio was 2.16: 1. Common clinical presentations included headache, fever, nausea or vomiting, and symptoms of common cold. On initial cerebrospinal fluid examination, white cell counts were above 500 cells/mm3 in 7 (18%) cases, and neutrophils predominated in 10 (28%) of 36 cases. The cerebrospinal fluid protein concentration was below 100 mg/dL in 29 (77%) of 38 cases, and hypoglycorrhachia (cerebrospinal fluid/serum glucose ratio 2 = 12.05, p=0.007). All patients were discharged uneventfully without receiving antibiotic therapy.

AB - A total of 38 adult cases of aseptic meningitis were diagnosed based on clinical manifestations as well as examination of cerebrospinal fluid at Kaohsiung Veterans General Hospital in 2001. The majority (31 cases, 82%) of cases occurred between June and August, and most (33 cases, 87%) of them aged from 18 to 35 years (median age, 25 years). The male-to-female ratio was 2.16: 1. Common clinical presentations included headache, fever, nausea or vomiting, and symptoms of common cold. On initial cerebrospinal fluid examination, white cell counts were above 500 cells/mm3 in 7 (18%) cases, and neutrophils predominated in 10 (28%) of 36 cases. The cerebrospinal fluid protein concentration was below 100 mg/dL in 29 (77%) of 38 cases, and hypoglycorrhachia (cerebrospinal fluid/serum glucose ratio 2 = 12.05, p=0.007). All patients were discharged uneventfully without receiving antibiotic therapy.

KW - Adult

KW - Aseptic meningitis

KW - Echovirus

KW - Outbreak

KW - Taiwan

UR - http://www.scopus.com/inward/record.url?scp=10744233441&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=10744233441&partnerID=8YFLogxK

M3 - Article

VL - 36

SP - 192

EP - 196

JO - Journal of Microbiology, Immunology and Infection

JF - Journal of Microbiology, Immunology and Infection

SN - 0253-2662

IS - 3

ER -