Abstract

This study estimates the risk of symptomatic nephrolithiasis within 5 years of newly diagnosed osteoporosis in a Taiwan population. This cohort study consisted of patients with a diagnosis of osteoporosis between Jan. 2003 and Dec. 2005 (N = 1634). Four age- and gender- matched patients for every patient in the study cohort were selected using random sampling as the comparison cohort (N = 6536). All patients were tracked for 5 years from the date of cohort entry to identify whether they developed symptomatic nephrolithiasis. Cox proportional hazard regressions were performed to evaluate the 5-year nephrolithiasis-free survival rates. During the 5-year follow-up period, 60 osteoporosis patients (3.7 %) and 165 non- osteoporosis patients (2.5 %) developed symptomatic nephrolithiasis. The adjusted HR of symptomatic nephrolithiasis was 1.38 times greater risk for patients with osteoporosis than for the comparison cohort (95% confidence interval (CI) 1.03–1.86; P 

Original languageEnglish
Pages (from-to)317-322
Number of pages6
JournalCalcified Tissue International
Volume95
Issue number4
DOIs
Publication statusPublished - 2014

Fingerprint

Nephrolithiasis
Taiwan
Osteoporosis
Population
Cohort Studies
Survival Rate
Confidence Intervals

Keywords

  • Asia population
  • Nephrolithiasis
  • Osteoporosis
  • Population-based study

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Medicine(all)

Cite this

Osteoporosis and the Risk of Symptomatic Nephrolithiasis : A Population-Based 5-Year Follow-Up Study in Taiwan. / Chou, Ping Song; Kuo, Chun Nan; Hung, Kuo Sheng; Chang, Wei Chiao; Liao, Yu Chien; Chi, Ying Chen; Chou, Wei Po; Tsai, Shih Jen; Liu, Mu En; Lai, Chiou Lian; Chou, Yii Her; Chang, Wei Pin.

In: Calcified Tissue International, Vol. 95, No. 4, 2014, p. 317-322.

Research output: Contribution to journalArticle

Chou, Ping Song ; Kuo, Chun Nan ; Hung, Kuo Sheng ; Chang, Wei Chiao ; Liao, Yu Chien ; Chi, Ying Chen ; Chou, Wei Po ; Tsai, Shih Jen ; Liu, Mu En ; Lai, Chiou Lian ; Chou, Yii Her ; Chang, Wei Pin. / Osteoporosis and the Risk of Symptomatic Nephrolithiasis : A Population-Based 5-Year Follow-Up Study in Taiwan. In: Calcified Tissue International. 2014 ; Vol. 95, No. 4. pp. 317-322.
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abstract = "This study estimates the risk of symptomatic nephrolithiasis within 5 years of newly diagnosed osteoporosis in a Taiwan population. This cohort study consisted of patients with a diagnosis of osteoporosis between Jan. 2003 and Dec. 2005 (N = 1634). Four age- and gender- matched patients for every patient in the study cohort were selected using random sampling as the comparison cohort (N = 6536). All patients were tracked for 5 years from the date of cohort entry to identify whether they developed symptomatic nephrolithiasis. Cox proportional hazard regressions were performed to evaluate the 5-year nephrolithiasis-free survival rates. During the 5-year follow-up period, 60 osteoporosis patients (3.7 {\%}) and 165 non- osteoporosis patients (2.5 {\%}) developed symptomatic nephrolithiasis. The adjusted HR of symptomatic nephrolithiasis was 1.38 times greater risk for patients with osteoporosis than for the comparison cohort (95{\%} confidence interval (CI) 1.03–1.86; P ",
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