Electronic prescribing i.e. e-prescribing is also known as Computerized Physician Order Entry (CPOE). It is a computer-aided system which offers the health professionals a robust platform for entering the prescription, recommended-tests, suggestions, etc. for the patients electronically rather than manually. Due to paucity of below-normal healthcare infrastructure and facilities in Pakistan which are available around the world in this modern world, there is an observable overburden on the health professionals and practitioners. Computerized Physician order entry (CPOE) system has shown to be very effective in minimizing the medication errors. Majority of the health professionals are of the view that CPOE is beneficial for both patient as well as health professionals themselves. They have shown a great deal of interest in the adoption of this new technology oriented system in our healthcare system. The results state clearly that this system is equally beneficial for organizations who want to adopt this system as perceived by the health professionals. Overall it supports the idea of adoption and implementation of CPOE in healthcare facilities in both public and private healthcare institutes. CPOE must be adopted to ease the healthcare system for patients as well as support healthcare professionals.