Optimization of drug cocktail on an integrated microfluidic system

Wen Yen Huang; Kuan Wang; Gwo Bin Lee

doi:10.1109/MEMSYS.2015.7051043

Optimization of drug cocktail on an integrated microfluidic system

Wen Yen Huang, Kuan Wang, Gwo Bin Lee

Research output: Contribution to journal › Conference article › peer-review

1 Citation (Scopus)

Abstract

Optimization of drug cocktails has been an important issue for a number of therapies of complicated diseases; however, it is an extremely task using traditional methods. Here we demonstrate a new microfluidic platform capable of automatically dispensing, mixing a small amount of drug combinations, and adding them to the cell cultures such that a precise and fine-tuned drug cocktails may be formed for the subsequent cell-level testing. Our proposed system could decrease manual bias and enhance the throughput of drug cocktail formulation on an automated and minituriazed microfluidic system.

Original language	English
Article number	7051043
Pages (from-to)	658-661
Number of pages	4
Journal	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume	2015-February
Issue number	February
DOIs	https://doi.org/10.1109/MEMSYS.2015.7051043
Publication status	Published - Feb 26 2015
Externally published	Yes
Event	2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal Duration: Jan 18 2015 → Jan 22 2015

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

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10.1109/MEMSYS.2015.7051043

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title = "Optimization of drug cocktail on an integrated microfluidic system",

abstract = "Optimization of drug cocktails has been an important issue for a number of therapies of complicated diseases; however, it is an extremely task using traditional methods. Here we demonstrate a new microfluidic platform capable of automatically dispensing, mixing a small amount of drug combinations, and adding them to the cell cultures such that a precise and fine-tuned drug cocktails may be formed for the subsequent cell-level testing. Our proposed system could decrease manual bias and enhance the throughput of drug cocktail formulation on an automated and minituriazed microfluidic system.",

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AU - Wang, Kuan

AU - Lee, Gwo Bin

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N2 - Optimization of drug cocktails has been an important issue for a number of therapies of complicated diseases; however, it is an extremely task using traditional methods. Here we demonstrate a new microfluidic platform capable of automatically dispensing, mixing a small amount of drug combinations, and adding them to the cell cultures such that a precise and fine-tuned drug cocktails may be formed for the subsequent cell-level testing. Our proposed system could decrease manual bias and enhance the throughput of drug cocktail formulation on an automated and minituriazed microfluidic system.

AB - Optimization of drug cocktails has been an important issue for a number of therapies of complicated diseases; however, it is an extremely task using traditional methods. Here we demonstrate a new microfluidic platform capable of automatically dispensing, mixing a small amount of drug combinations, and adding them to the cell cultures such that a precise and fine-tuned drug cocktails may be formed for the subsequent cell-level testing. Our proposed system could decrease manual bias and enhance the throughput of drug cocktail formulation on an automated and minituriazed microfluidic system.

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JF - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

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ER -

Optimization of drug cocktail on an integrated microfluidic system

Abstract

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