Optimization of drug cocktail on an integrated microfluidic system

Wen Yen Huang, Kuan Wang, Gwo Bin Lee

Research output: Contribution to journalConference article

1 Citation (Scopus)

Abstract

Optimization of drug cocktails has been an important issue for a number of therapies of complicated diseases; however, it is an extremely task using traditional methods. Here we demonstrate a new microfluidic platform capable of automatically dispensing, mixing a small amount of drug combinations, and adding them to the cell cultures such that a precise and fine-tuned drug cocktails may be formed for the subsequent cell-level testing. Our proposed system could decrease manual bias and enhance the throughput of drug cocktail formulation on an automated and minituriazed microfluidic system.

Original languageEnglish
Article number7051043
Pages (from-to)658-661
Number of pages4
JournalProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume2015-February
Issue numberFebruary
DOIs
Publication statusPublished - Feb 26 2015
Externally publishedYes
Event2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal
Duration: Jan 18 2015Jan 22 2015

Fingerprint

Fluidic devices
Disease control
Cell culture
Microfluidics
Mechanics
Drug Combinations
Pharmaceutical Preparations
Throughput
Testing
Pharmaceutical Chemistry

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Optimization of drug cocktail on an integrated microfluidic system. / Huang, Wen Yen; Wang, Kuan; Lee, Gwo Bin.

In: Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Vol. 2015-February, No. February, 7051043, 26.02.2015, p. 658-661.

Research output: Contribution to journalConference article

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