On pump versus off pump coronary artery bypass grafting in patients with end-stage renal disease and coronary artery disease — A nation-wide, propensity score matched database analyses

Jien Jiun Chen, Lian Yu Lin, Yao Hsu Yang, Juey Jen Hwang, Pau Chung Chen, Jiunn Lee Lin, Nai Hsin Chi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective The usage of on or off cardiopulmonary bypass in patients with coronary artery disease receiving coronary artery bypass grafting (CABG) surgery had been debated and had not yet been investigated thoroughly in patients with end-stage renal disease (ESRD). We aimed to study cardiovascular outcomes and total mortality in these patients by using our National Health Insurance (NHI) database. Method By using our NHI ESRD claim database, we searched ESRD patients aged more than 18 years, who received CABG and divided them into on pump and off pump groups. Baseline characteristics and underlying comorbidities were identified from the database. Propensity score (PS) method was used to match all the potential confounders between patients. Outcomes including mortality, myocardial infarction, stroke and repeat revascularization within 30 days, 1 year and whole follow-up period were also obtained. Result A total of 134,410 ESRD patients were identified in the database. We included 341 patients and 543 patients who received off pump and on pump CABG respectively. The hazard ratios of different outcomes at 30 days, 1 year and a median of 745 days after CABG did not show significant different between on, or off pump groups before and after PS match. Conclusion ESRD patients with CAD undergoing either on pump or off pump CABG surgery showed similar outcomes in 30 days, 1 year and whole follow-up period.

Original languageEnglish
Pages (from-to)529-534
Number of pages6
JournalInternational Journal of Cardiology
Volume227
DOIs
Publication statusPublished - Jan 15 2017
Externally publishedYes

Fingerprint

Off-Pump Coronary Artery Bypass
Propensity Score
Renal Artery
Coronary Artery Bypass
Chronic Kidney Failure
Coronary Artery Disease
Databases
National Health Programs
Mortality
Cardiopulmonary Bypass
Comorbidity
Stroke
Myocardial Infarction
Outcome Assessment (Health Care)

Keywords

  • Coronary artery bypass grafting
  • Coronary artery disease
  • End-stage renal disease
  • Off pump
  • On pump

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

On pump versus off pump coronary artery bypass grafting in patients with end-stage renal disease and coronary artery disease — A nation-wide, propensity score matched database analyses. / Chen, Jien Jiun; Lin, Lian Yu; Yang, Yao Hsu; Hwang, Juey Jen; Chen, Pau Chung; Lin, Jiunn Lee; Chi, Nai Hsin.

In: International Journal of Cardiology, Vol. 227, 15.01.2017, p. 529-534.

Research output: Contribution to journalArticle

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