On-pump beating-heart coronary artery bypass provides efficacious short- and long-term outcomes in hemodialysis patients.

Yi Ting Tsai, Feng-Yen Lin, Ching Huang Lai, Yi Chang Lin, Chih Yuan Lin, Chien Sung Tsai

Research output: Contribution to journalArticle

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Abstract

On-pump beating-heart coronary artery bypass grafting surgery (CABG) is beneficial due to the elimination of cardioplegic arrest. However, there are few reports regarding its efficacy in chronic hemodialysis patients. This study investigated the potential benefits of on-pump beating-heart CABG in chronic hemodialysis patients. From January 2002 to January 2010, 186 patients with chronic hemodialysis underwent CABG in our institution. In total, 82 patients underwent conventional CABG with cardioplegic arrest, 56 underwent off-pump CABG and 48 underwent on-pump beating-heart CABG. The early results and long-term outcomes were compared among these three groups. On-pump beating-heart CABG significantly reduced the duration of cardiopulmonary bypass (CPB) compared with conventional CABG. The post-operative pericardial drainage amount (P <0.01), length of hospital stay (P <0.001) and length of post-operative intensive care unit stay (P <0.001) were significantly lower in the on-pump beating-heart and off-pump CABG groups than in the conventional CABG group. No significant difference was found regarding 30-day mortality and morbidity rates including stroke, pneumonia, arrhythmia, intestinal complication and low cardiac output syndrome. There were no statistical differences in the freedom from cardiac events (P = 0.323), but on-pump beating-heart CABG provided better long-term survival than conventional CABG (P = 0.009). On-pump beating-heart CABG is a safe procedure that provides optimal operative exposure in chronic hemodialysis patients. The use of CPB and the elimination of cardioplegic arrest may be beneficial for the short- and long-term survival of chronic hemodialysis patients.

Original languageEnglish
Pages (from-to)2059-2065
Number of pages7
JournalNephrology Dialysis Transplantation
Volume27
Issue number5
Publication statusPublished - May 2012
Externally publishedYes

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Off-Pump Coronary Artery Bypass
Coronary Artery Bypass
Renal Dialysis
Cardiopulmonary Bypass

ASJC Scopus subject areas

  • Medicine(all)

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On-pump beating-heart coronary artery bypass provides efficacious short- and long-term outcomes in hemodialysis patients. / Tsai, Yi Ting; Lin, Feng-Yen; Lai, Ching Huang; Lin, Yi Chang; Lin, Chih Yuan; Tsai, Chien Sung.

In: Nephrology Dialysis Transplantation, Vol. 27, No. 5, 05.2012, p. 2059-2065.

Research output: Contribution to journalArticle

Tsai, Yi Ting ; Lin, Feng-Yen ; Lai, Ching Huang ; Lin, Yi Chang ; Lin, Chih Yuan ; Tsai, Chien Sung. / On-pump beating-heart coronary artery bypass provides efficacious short- and long-term outcomes in hemodialysis patients. In: Nephrology Dialysis Transplantation. 2012 ; Vol. 27, No. 5. pp. 2059-2065.
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