Obstructive sleep apnea and urological comorbidities in males: a population-based study

Shiu Dong Chung, Shih Han Hung, Herng Ching Lin, Ming Chieh Tsai, Li Ting Kao

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Purpose: This study aimed to investigate associations between obstructive sleep apnea (OSA) and urological comorbidities using a large population-based dataset. Methods: This cross-sectional study used the Taiwan Longitudinal Health Insurance Database 2005. We included 1236 males with OSA in the study group and 4944 males without OSA in the comparison group. Conditional logistic regressions were performed to examine relationships between OSA and urological comorbidities. Results: We found that patients with OSA had significantly greater prevalences of hypertrophy of the prostate (15.13 vs. 7.28 %), chronic prostatitis (4.37 vs. 2.16 %,), urinary incontinence (3.32 vs. 0.87 %), nocturia (2.02 vs. 0.61 %), erectile dysfunction (2.91 vs. 0.97 %), urinary calculi (12.06 vs. 6.80 %), and prostate cancer (0.97 vs. 0.40 %) than the comparison group. Additionally, the adjusted odds ratios in males with OSA for hypertrophy of prostate, chronic prostatitis, urinary incontinence, nocturia, erectile dysfunction, urinary calculi, and prostate cancer were 2.54 (95 % confidence interval (CI) 2.05~3.15), 1.95 (95 % CI 1.38~2.74), 4.13 (95 % CI 2.63~6.50), 3.54 (95 % CI 2.03~6.18), 2.95 (95 % CI 1.89~4.61), 1.89 (95 % CI 1.53~2.33), and 2.14 (95 % CI 1.03~4.43) than those without OSA, respectively. Conclusions: This study concluded that males with OSA had higher odds ratios of hypertrophy of the prostate, chronic prostatitis, urinary incontinence, nocturia, erectile dysfunction, urinary calculi, and prostate cancer than comparison group.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalSleep and Breathing
DOIs
Publication statusAccepted/In press - Apr 7 2016

Fingerprint

Obstructive Sleep Apnea
Comorbidity
Confidence Intervals
Nocturia
Prostatitis
Urinary Calculi
Population
Urinary Incontinence
Erectile Dysfunction
Hypertrophy
Prostate
Prostatic Neoplasms
Odds Ratio
Health Insurance
Taiwan
Cross-Sectional Studies
Logistic Models
Databases

Keywords

  • Comorbidity
  • Obstructive sleep apnea
  • Prostate
  • Prostatitis
  • Urology

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Clinical Neurology

Cite this

Obstructive sleep apnea and urological comorbidities in males : a population-based study. / Chung, Shiu Dong; Hung, Shih Han; Lin, Herng Ching; Tsai, Ming Chieh; Kao, Li Ting.

In: Sleep and Breathing, 07.04.2016, p. 1-6.

Research output: Contribution to journalArticle

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abstract = "Purpose: This study aimed to investigate associations between obstructive sleep apnea (OSA) and urological comorbidities using a large population-based dataset. Methods: This cross-sectional study used the Taiwan Longitudinal Health Insurance Database 2005. We included 1236 males with OSA in the study group and 4944 males without OSA in the comparison group. Conditional logistic regressions were performed to examine relationships between OSA and urological comorbidities. Results: We found that patients with OSA had significantly greater prevalences of hypertrophy of the prostate (15.13 vs. 7.28 {\%}), chronic prostatitis (4.37 vs. 2.16 {\%},), urinary incontinence (3.32 vs. 0.87 {\%}), nocturia (2.02 vs. 0.61 {\%}), erectile dysfunction (2.91 vs. 0.97 {\%}), urinary calculi (12.06 vs. 6.80 {\%}), and prostate cancer (0.97 vs. 0.40 {\%}) than the comparison group. Additionally, the adjusted odds ratios in males with OSA for hypertrophy of prostate, chronic prostatitis, urinary incontinence, nocturia, erectile dysfunction, urinary calculi, and prostate cancer were 2.54 (95 {\%} confidence interval (CI) 2.05~3.15), 1.95 (95 {\%} CI 1.38~2.74), 4.13 (95 {\%} CI 2.63~6.50), 3.54 (95 {\%} CI 2.03~6.18), 2.95 (95 {\%} CI 1.89~4.61), 1.89 (95 {\%} CI 1.53~2.33), and 2.14 (95 {\%} CI 1.03~4.43) than those without OSA, respectively. Conclusions: This study concluded that males with OSA had higher odds ratios of hypertrophy of the prostate, chronic prostatitis, urinary incontinence, nocturia, erectile dysfunction, urinary calculi, and prostate cancer than comparison group.",
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AU - Chung, Shiu Dong

AU - Hung, Shih Han

AU - Lin, Herng Ching

AU - Tsai, Ming Chieh

AU - Kao, Li Ting

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N2 - Purpose: This study aimed to investigate associations between obstructive sleep apnea (OSA) and urological comorbidities using a large population-based dataset. Methods: This cross-sectional study used the Taiwan Longitudinal Health Insurance Database 2005. We included 1236 males with OSA in the study group and 4944 males without OSA in the comparison group. Conditional logistic regressions were performed to examine relationships between OSA and urological comorbidities. Results: We found that patients with OSA had significantly greater prevalences of hypertrophy of the prostate (15.13 vs. 7.28 %), chronic prostatitis (4.37 vs. 2.16 %,), urinary incontinence (3.32 vs. 0.87 %), nocturia (2.02 vs. 0.61 %), erectile dysfunction (2.91 vs. 0.97 %), urinary calculi (12.06 vs. 6.80 %), and prostate cancer (0.97 vs. 0.40 %) than the comparison group. Additionally, the adjusted odds ratios in males with OSA for hypertrophy of prostate, chronic prostatitis, urinary incontinence, nocturia, erectile dysfunction, urinary calculi, and prostate cancer were 2.54 (95 % confidence interval (CI) 2.05~3.15), 1.95 (95 % CI 1.38~2.74), 4.13 (95 % CI 2.63~6.50), 3.54 (95 % CI 2.03~6.18), 2.95 (95 % CI 1.89~4.61), 1.89 (95 % CI 1.53~2.33), and 2.14 (95 % CI 1.03~4.43) than those without OSA, respectively. Conclusions: This study concluded that males with OSA had higher odds ratios of hypertrophy of the prostate, chronic prostatitis, urinary incontinence, nocturia, erectile dysfunction, urinary calculi, and prostate cancer than comparison group.

AB - Purpose: This study aimed to investigate associations between obstructive sleep apnea (OSA) and urological comorbidities using a large population-based dataset. Methods: This cross-sectional study used the Taiwan Longitudinal Health Insurance Database 2005. We included 1236 males with OSA in the study group and 4944 males without OSA in the comparison group. Conditional logistic regressions were performed to examine relationships between OSA and urological comorbidities. Results: We found that patients with OSA had significantly greater prevalences of hypertrophy of the prostate (15.13 vs. 7.28 %), chronic prostatitis (4.37 vs. 2.16 %,), urinary incontinence (3.32 vs. 0.87 %), nocturia (2.02 vs. 0.61 %), erectile dysfunction (2.91 vs. 0.97 %), urinary calculi (12.06 vs. 6.80 %), and prostate cancer (0.97 vs. 0.40 %) than the comparison group. Additionally, the adjusted odds ratios in males with OSA for hypertrophy of prostate, chronic prostatitis, urinary incontinence, nocturia, erectile dysfunction, urinary calculi, and prostate cancer were 2.54 (95 % confidence interval (CI) 2.05~3.15), 1.95 (95 % CI 1.38~2.74), 4.13 (95 % CI 2.63~6.50), 3.54 (95 % CI 2.03~6.18), 2.95 (95 % CI 1.89~4.61), 1.89 (95 % CI 1.53~2.33), and 2.14 (95 % CI 1.03~4.43) than those without OSA, respectively. Conclusions: This study concluded that males with OSA had higher odds ratios of hypertrophy of the prostate, chronic prostatitis, urinary incontinence, nocturia, erectile dysfunction, urinary calculi, and prostate cancer than comparison group.

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