Nutraceutical encapsulation and delivery system for type 2 diabetes mellitus

Navneet Kumar Dubey, Abhinay Kumar Singh, Rajni Dubey, Win Ping Deng

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Type 2 diabetes mellitus (T2DM) is multifactorial metabolic disorder associated with dysfunction of pancreatic β cells, resulting in impaired insulin signaling, abnormal glucose metabolism, and increased oxidative stress. Current nutraceutical therapies for T2DM are facing great challenges such as adverse effects; therefore, the novel techniques are being considered to achieve sufficient therapeutic outcomes. The nutraceuticals are biological molecules derived from various plant species and known for their beneficial therapeutic effects. These include vitamins, antioxidants, amino acids, and fatty acids that are used to prevent disease and control the symptoms. However, their therapeutic ability gets reduced with advancement of time. As a consequence, encapsulation techniques are being considered to retain their properties by slow degradation. In this chapter, we will discuss about various nutraceuticals and their encapsulation aiming for treatment of T2DM.

Original languageEnglish
Title of host publicationBiopolymer-Based Formulations
Subtitle of host publicationBiomedical and Food Applications
PublisherElsevier
Pages353-363
Number of pages11
ISBN (Electronic)9780128168981
ISBN (Print)9780128168974
DOIs
Publication statusPublished - Jan 23 2020

Keywords

  • Encapsulation
  • Nutraceutical
  • Polyphenolics
  • Spray drying
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Engineering(all)
  • Materials Science(all)

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