Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma

Medicine & Life Sciences

• MPT0B098 100%
• Squamous Cell Carcinoma of Head and Neck 45%
• Epithelial-Mesenchymal Transition 42%
• Microtubules 39%
• Hypoxia 32%
• Hypoxia-Inducible Factor 1 14%
• Transforming Growth Factors 12%
• Activating Transcription Factors 8%
• Down-Regulation 8%
• Phosphorylation 8%
• Gastropoda 7%
• Tumor Hypoxia 7%
• Focal Adhesion Protein-Tyrosine Kinases 7%
• Methylene Blue 6%
• Messenger RNA 6%
• Vimentin 6%
• Reverse Transcriptase Polymerase Chain Reaction 5%
• Cadherins 5%
• Head and Neck Neoplasms 5%
• Inhibitory Concentration 50 5%
• Wound Healing 5%
• Fluorescent Antibody Technique 5%
• Actins 4%
• Coloring Agents 4%
• Western Blotting 3%
• Staining and Labeling 3%
• Antigens 3%
• Neoplasm Metastasis 3%
• Cell Line 3%
• In Vitro Techniques 2%
• Proteins 2%
• Neoplasms 1%
• Therapeutics 0%

Chemical Compounds

• Western Blotting 25%
• Chain Reaction 20%
• Antitumor 18%
• Marker 17%
• Methylene Blue 17%
• Antigen 17%
• Dye 12%
• Protein 8%