No association of alpha-2 macroglobulin gene five-nucleotide deletion with AD in Taiwan Chinese

C. J. Hu, S. M. Sung, H. C. Liu, K. Y. Lee, W. C. Hsu, W. K. Wong, C. C. Lee, C. H. Tsai, Jan Gowth Chang

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22 Citations (Scopus)

Abstract

The alpha-2 macroglobulin five-nucleotide deletion (A2M-2) allele frequency was not significantly higher in the AD group than the control group (0.062 versus 0.101, p > 0.1). The odds ratio for AD in individuals with the A2M-2 allele was 0.582 (95% CI, 0.25 to 1.40). These results do not support the association between A2M-2 and AD in the Chinese population, although the allele frequency of A2M-2 is lower than that found in the Caucasian population. Therefore, A2M-2 might not be a significant risk factor of AD among Taiwan Chinese.

Original languageEnglish
Pages (from-to)642-643
Number of pages2
JournalNeurology
Volume53
Issue number3
Publication statusPublished - Aug 11 1999
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

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