Nicotine-induced hyperlocomotion is not modified by the estrous cycle, ovariectomy and estradiol replacement at physiological level

Dong Yih Kuo; Tzer Bin Lin; Chiun Chien Huang; Sheau Ling Duh; Jiuan Miau Liao; Juei Tang Cheng

Nicotine-induced hyperlocomotion is not modified by the estrous cycle, ovariectomy and estradiol replacement at physiological level

Dong Yih Kuo, Tzer Bin Lin, Chiun Chien Huang, Sheau Ling Duh, Jiuan Miau Liao, Juei Tang Cheng

Research output: Contribution to journal › Article › peer-review

Abstract

The present study was designed to investigate whether nicotine's effect on locomotion might be modulated by the ovarian hormone at physiological level. Rats at normal cycling of estrus and diestrus were selected for the comparison of nicotine-induced hyperlocomotion based on the document that the release of striatal dopamine was greatest at the estrous phase. Ovariectomized rats primed with or without estrogen at physiological level were also selected for comparison. Increase in spontaneous locomotion by nicotine was statistically significant at the doses of 0.15 and 0.3 mg/kg (P

Original language	English
Pages (from-to)	83-88
Number of pages	6
Journal	Chinese Journal of Physiology
Volume	42
Issue number	2
Publication status	Published - 1999
Externally published	Yes

Keywords

Dopaminergic system
Estrous cycle
Locomotor behavior
Nicotine
Ovariectomy

ASJC Scopus subject areas

Physiology

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Nicotine-induced hyperlocomotion is not modified by the estrous cycle, ovariectomy and estradiol replacement at physiological level. / Kuo, Dong Yih; Lin, Tzer Bin; Huang, Chiun Chien; Duh, Sheau Ling; Liao, Jiuan Miau; Cheng, Juei Tang.

In: Chinese Journal of Physiology, Vol. 42, No. 2, 1999, p. 83-88.

Research output: Contribution to journal › Article › peer-review

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AU - Duh, Sheau Ling

AU - Liao, Jiuan Miau

AU - Cheng, Juei Tang

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KW - Estrous cycle

KW - Locomotor behavior

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KW - Ovariectomy

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Nicotine-induced hyperlocomotion is not modified by the estrous cycle, ovariectomy and estradiol replacement at physiological level

Abstract

Keywords

ASJC Scopus subject areas

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