An adequate thickness and pattern of the pre-ovulatory endometrium is considered one of the essential requirements for a successful pregnancy.Although various methods for increasing endometrial thickness have been proposed, the real value of these interventions remains controversial. Here, we present a case of successful administration of extended estrogen supplementation before conventional controlled ovarian hyperstimulation in a woman who had experienced repeated implantation failure because of an unresponsive thin endometrium. After the estrogen supplement was administrated for an extended period, the in vitro fertilization/embryo transfer in this patient led to an uneventful twin pregnancy and delivery at term.
- Extended estrogen supplementation
- Ovarian hyperstimulation
- Thin endometrium
ASJC Scopus subject areas
- Obstetrics and Gynaecology